You are here

Article Text

Article menu

Download PDFPDF

Research Article
Paternal origin of the de novo deleted chromosome 4 in Wolf-Hirschhorn syndrome.
  1. R Tupler,
  2. L Bortotto,
  3. E M Bühler,
  4. M Alkan,
  5. N J Malik,
  6. N Bösch-Al Jadooa,
  7. L Memo,
  8. P Maraschio
  1. Genetisches Labor, Universitats-Kinderklinik, Basel, Switzerland.

    Abstract

    The parental origin of the de novo deleted chromosome 4 was studied in five cases of Wolf-Hirschhorn syndrome using polymorphic probes mapping in the 4p16.3 region. In all the patients the deleted chromosome was found to be of paternal origin and these results, together with similar ones obtained by another group, make the preferential paternal origin of the de novo chromosome 4 deletion highly significant.

    https://doi.org/10.1136/jmg.29.1.53

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.