[HTML][HTML] Newcastle disease virus infection triggers HMGB1 release to promote the inflammatory response

Y Qu, Y Zhan, S Yang, S Ren, X Qiu, ZU Rehamn… - Virology, 2018 - Elsevier
High mobility group box 1 (HMGB1) is a key member of the “danger associated molecular
patterns”(DAMPs) which plays important roles in systemic inflammation and has a …

Profiling of the genetic features of Chinese patients with gastric cancer with HRD germline mutations in a large-scale retrospective study

C Zhang, D Zhu, Y Qu, M Shi, J Ma, Y Peng… - Journal of Medical …, 2023 - jmg.bmj.com
Background Approximately 10% of gastric cancers (GCs) are associated with strong familial
clustering and can be attributed to genetic predisposition. Homologous recombination …

Syncytia generated by hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus induce complete autophagy by activating AMPK …

S Ren, ZU Rehman, M Shi, B Yang, Y Qu, XF Yang… - Veterinary …, 2019 - Elsevier
Autophagy triggered by glycoprotein-mediated membrane fusion has been reported for
several paramyxoviruses. However, the function of HN and F glycoproteins of NDV and their …

[HTML][HTML] Hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus cooperatively disturb fusion–fission homeostasis to enhance …

S Ren, ZU Rehman, M Shi, B Yang, P Liu, Y Yin… - Veterinary …, 2019 - Springer
The fusogenically activated F and HN proteins of virulent NDV induce complete autophagic
flux in DF-1 and A549 cells. However, the effect of both glycoproteins on mitochondria …

Specific Monoclonal Antibodies Recognizing the Endogenous Chicken High Mobility Group Box 1 Protein

Y Qu, Y Zhan, S Yang, X Qiu, L Tan, Y Sun… - Monoclonal …, 2017 - liebertpub.com
High mobility group box 1 (HMGB1) is a key member of the “danger associated molecular
patterns”(DAMPs), which can localize in various compartments of the cell, and plays …

Early age of onset of double germline DDR-mutated gastric cancer

Y Qu, M Shi, Y Liang, B Zhu - Cancer Research, 2022 - AACR
Background: Gastric cancer (GC) is one of the leading causes of cancer death in China.
Approximately 10% of GC cases are associated with strong familial clustering and can be …

Influence of the ubiquitin-proteasome system on NDV replication in DF-1 cells.

YR Qu, Y Zhan, XS Qiu, L Tan, YJ Sun… - Chinese Veterinary …, 2017 - cabdirect.org
In order to investigate whether the ubiquitin-proteasome system (UPS) of DF-1 cells was
involved in the replication of Newcastle disease virus (NDV) in DF1 cells, Herts/33 strain …

Development of double antibodies sandwich ELISA for detection of chicken HMGB1 protein.

YR Qu, Y Zhan, XS Qiu, C Ding - Zhongguo Yufang Shouyi Xuebao …, 2018 - cabdirect.org
In order to establish double antibodies sandwich ELISA (DAS-ELISA) for detection of
chicken HMGB1 protein (chHMGB1), the soluble form recombiant chHMGB1 protein …

Akt/mTOR/4E-BP1 and p38/Erk/Mnk1 signaling pathways regulates translation initiation factor 4E activation in the early stage of NDV infection.

Y Zhan, XS Qiu, YR Qu, YJ Sun, L Tan… - … /Chinese Journal of …, 2015 - cabdirect.org
To determine the effect of Newcastle disease virus (NDV) infection on host translation
machinery and associated signaling pathways, the phosphorylation of host translation …

Urine based dynamically monitoring reflect pathologic response in MIBC patients with neoadjuvant immunotherapy

X Yang, L Cai, Q Cao, M Shi, Y Liang, Y Qu, Q Lu - Cancer Research, 2022 - AACR
Background: The recommended standard of care treatment for nonmetastatic muscle-
invasive bladder cancer (MIBC) is radical cystectomy (RC). Even with urinary diversion …