[PDF][PDF] Delineating COVID-19 immunological features using single-cell RNA sequencing
Understanding the molecular mechanisms of coronavirus disease 2019 (COVID-19)
pathogenesis and immune response is vital for developing therapies. Single-cell RNA …
pathogenesis and immune response is vital for developing therapies. Single-cell RNA …
[HTML][HTML] Anti-colorectal cancer effects of seaweed-derived bioactive compounds
Y Fu, D Xie, Y Zhu, X Zhang, H Yue, K Zhu, Z Pi… - Frontiers in …, 2022 - frontiersin.org
Seaweeds are classified as Chlorophyta, Rhodophyta, and Phaeophyta. They constitute a
number of the most significant repositories of new therapeutic compounds for human use …
number of the most significant repositories of new therapeutic compounds for human use …
[HTML][HTML] Improvements and impacts of GRCh38 human reference on high throughput sequencing data analysis
Analyses of high throughput sequencing data starts with alignment against a reference
genome, which is the foundation for all re-sequencing data analyses. Each new release of …
genome, which is the foundation for all re-sequencing data analyses. Each new release of …
[HTML][HTML] Gene2vec: distributed representation of genes based on co-expression
Background Existing functional description of genes are categorical, discrete, and mostly
through manual process. In this work, we explore the idea of gene embedding, distributed …
through manual process. In this work, we explore the idea of gene embedding, distributed …
WebCSEA: web-based cell-type-specific enrichment analysis of genes
Human complex traits and common diseases show tissue-and cell-type-specificity. Recently,
single-cell RNA sequencing (scRNA-seq) technology has successfully depicted cellular …
single-cell RNA sequencing (scRNA-seq) technology has successfully depicted cellular …
[HTML][HTML] Deep generative neural network for accurate drug response imputation
Drug response differs substantially in cancer patients due to inter-and intra-tumor
heterogeneity. Particularly, transcriptome context, especially tumor microenvironment, has …
heterogeneity. Particularly, transcriptome context, especially tumor microenvironment, has …
[HTML][HTML] Microbial transformation of ginsenoside Rb1, Re and Rg1 and its contribution to the improved anti-inflammatory activity of ginseng
S Yu, X Zhou, F Li, C Xu, F Zheng, J Li, H Zhao… - Scientific Reports, 2017 - nature.com
Microbial transformation of ginsenosides to increase its pharmaceutical effect is gaining
increasing attention in recent years. In this study, Cellulosimicrobium sp. TH-20, which was …
increasing attention in recent years. In this study, Cellulosimicrobium sp. TH-20, which was …
[PDF][PDF] A genome-wide association study discovers 46 loci of the human metabolome in the Hispanic Community Health Study/Study of Latinos
Variation in levels of the human metabolome reflect changes in homeostasis, providing a
window into health and disease. The genetic impact on circulating metabolites in Hispanics …
window into health and disease. The genetic impact on circulating metabolites in Hispanics …
[HTML][HTML] Association of CXCR6 with COVID-19 severity: delineating the host genetic factors in transcriptomic regulation
Abstract The coronavirus disease 2019 (COVID-19) is an infectious disease that mainly
affects the host respiratory system with~ 80% asymptomatic or mild cases and~ 5% severe …
affects the host respiratory system with~ 80% asymptomatic or mild cases and~ 5% severe …
Age-associated telomere attrition in adipocyte progenitors predisposes to metabolic disease
White and beige adipocytes in subcutaneous adipose tissue (SAT) and visceral adipose
tissue (VAT) are maintained by proliferation and differentiation of adipose progenitor cells …
tissue (VAT) are maintained by proliferation and differentiation of adipose progenitor cells …