User profiles for "author:Yulin Dai"

Yulin Dai

- Verified email at uth.tmc.edu - Cited by 1025

Yulin Dai

- Verified email at ccucm.edu.cn - Cited by 558

[PDF][PDF] Delineating COVID-19 immunological features using single-cell RNA sequencing

W Liu, J Jia, Y Dai, W Chen, G Pei, Q Yan, Z Zhao - The Innovation, 2022 - cell.com
Understanding the molecular mechanisms of coronavirus disease 2019 (COVID-19)
pathogenesis and immune response is vital for developing therapies. Single-cell RNA …

[HTML][HTML] Anti-colorectal cancer effects of seaweed-derived bioactive compounds

Y Fu, D Xie, Y Zhu, X Zhang, H Yue, K Zhu, Z Pi… - Frontiers in …, 2022 - frontiersin.org
Seaweeds are classified as Chlorophyta, Rhodophyta, and Phaeophyta. They constitute a
number of the most significant repositories of new therapeutic compounds for human use …

[HTML][HTML] Improvements and impacts of GRCh38 human reference on high throughput sequencing data analysis

Y Guo, Y Dai, H Yu, S Zhao, DC Samuels, Y Shyr - Genomics, 2017 - Elsevier
Analyses of high throughput sequencing data starts with alignment against a reference
genome, which is the foundation for all re-sequencing data analyses. Each new release of …

[HTML][HTML] Gene2vec: distributed representation of genes based on co-expression

J Du, P Jia, Y Dai, C Tao, Z Zhao, D Zhi - BMC genomics, 2019 - Springer
Background Existing functional description of genes are categorical, discrete, and mostly
through manual process. In this work, we explore the idea of gene embedding, distributed …

WebCSEA: web-based cell-type-specific enrichment analysis of genes

Y Dai, R Hu, A Liu, KS Cho, AM Manuel… - Nucleic acids …, 2022 - academic.oup.com
Human complex traits and common diseases show tissue-and cell-type-specificity. Recently,
single-cell RNA sequencing (scRNA-seq) technology has successfully depicted cellular …

[HTML][HTML] Deep generative neural network for accurate drug response imputation

P Jia, R Hu, G Pei, Y Dai, YY Wang, Z Zhao - Nature communications, 2021 - nature.com
Drug response differs substantially in cancer patients due to inter-and intra-tumor
heterogeneity. Particularly, transcriptome context, especially tumor microenvironment, has …

[HTML][HTML] Microbial transformation of ginsenoside Rb1, Re and Rg1 and its contribution to the improved anti-inflammatory activity of ginseng

S Yu, X Zhou, F Li, C Xu, F Zheng, J Li, H Zhao… - Scientific Reports, 2017 - nature.com
Microbial transformation of ginsenosides to increase its pharmaceutical effect is gaining
increasing attention in recent years. In this study, Cellulosimicrobium sp. TH-20, which was …

[PDF][PDF] A genome-wide association study discovers 46 loci of the human metabolome in the Hispanic Community Health Study/Study of Latinos

EV Feofanova, H Chen, Y Dai, P Jia, ML Grove… - The American Journal of …, 2020 - cell.com
Variation in levels of the human metabolome reflect changes in homeostasis, providing a
window into health and disease. The genetic impact on circulating metabolites in Hispanics …

[HTML][HTML] Association of CXCR6 with COVID-19 severity: delineating the host genetic factors in transcriptomic regulation

Y Dai, J Wang, HH Jeong, W Chen, P Jia, Z Zhao - Human genetics, 2021 - Springer
Abstract The coronavirus disease 2019 (COVID-19) is an infectious disease that mainly
affects the host respiratory system with~ 80% asymptomatic or mild cases and~ 5% severe …

Age-associated telomere attrition in adipocyte progenitors predisposes to metabolic disease

Z Gao, AC Daquinag, C Fussell, Z Zhao, Y Dai… - Nature …, 2020 - nature.com
White and beige adipocytes in subcutaneous adipose tissue (SAT) and visceral adipose
tissue (VAT) are maintained by proliferation and differentiation of adipose progenitor cells …