User profiles for "author:Yoon Shin Cho"
Yoon Shin ChoHallym University Biomedical Science Professor Verified email at hallym.ac.kr Cited by 21050 |
Biological, clinical and population relevance of 95 loci for blood lipids
TM Teslovich, K Musunuru, AV Smith, AC Edmondson… - Nature, 2010 - nature.com
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density
lipoprotein cholesterol and triglycerides are among the most important risk factors for …
lipoprotein cholesterol and triglycerides are among the most important risk factors for …
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits
YS Cho, MJ Go, YJ Kim, JY Heo, JH Oh, HJ Ban… - Nature …, 2009 - nature.com
To identify genetic factors influencing quantitative traits of biomedical importance, we
conducted a genome-wide association study in 8,842 samples from population-based …
conducted a genome-wide association study in 8,842 samples from population-based …
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
CKDGen Consortium, KidneyGen Consortium… - Nature, 2011 - nature.com
Blood pressure is a heritable trait influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥ 140 mm …
to environmental stimuli. Over one billion people worldwide have hypertension (≥ 140 mm …
Implication of Genetic Variants Near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in Type 2 Diabetes and Obesity in 6,719 Asians
OBJECTIVE—Recent genome-wide association studies have identified six novel genes for
type 2 diabetes and obesity and confirmed TCF7L2 as the major type 2 diabetes gene to …
type 2 diabetes and obesity and confirmed TCF7L2 as the major type 2 diabetes gene to …
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians
We conducted a three-stage genetic study to identify susceptibility loci for type 2 diabetes
(T2D) in east Asian populations. We followed our stage 1 meta-analysis of eight T2D …
(T2D) in east Asian populations. We followed our stage 1 meta-analysis of eight T2D …
Identification of type 2 diabetes loci in 433,540 East Asian individuals
Meta-analyses of genome-wide association studies (GWAS) have identified more than 240
loci that are associated with type 2 diabetes (T2D),; however, most of these loci have been …
loci that are associated with type 2 diabetes (T2D),; however, most of these loci have been …
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians
We conducted a meta-analysis of genome-wide association studies of systolic (SBP) and
diastolic (DBP) blood pressure in 19,608 subjects of east Asian ancestry from the AGEN-BP …
diastolic (DBP) blood pressure in 19,608 subjects of east Asian ancestry from the AGEN-BP …
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits
To identify the genetic bases for nine metabolic traits, we conducted a meta-analysis
combining Korean genome-wide association results from the KARE project (n= 8,842) and …
combining Korean genome-wide association results from the KARE project (n= 8,842) and …
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
Loss-of-function mutations protective against human disease provide in vivo validation of
therapeutic targets,,, but none have yet been described for type 2 diabetes (T2D). Through …
therapeutic targets,,, but none have yet been described for type 2 diabetes (T2D). Through …
A genome-wide association study of gestational diabetes mellitus in Korean women
Knowledge regarding the genetic risk loci for gestational diabetes mellitus (GDM) is still
limited. In this study, we performed a two-stage genome-wide association analysis in Korean …
limited. In this study, we performed a two-stage genome-wide association analysis in Korean …