Homozygous mutations in DZIP1 can induce asthenoteratospermia with severe MMAF

M Lv, W Liu, W Chi, X Ni, J Wang, H Cheng… - Journal of medical …, 2020 - jmg.bmj.com
Background Asthenoteratospermia, one of the most common causes for male infertility, often
presents with defective sperm heads and/or flagella. Multiple morphological abnormalities of …

[HTML][HTML] NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation

M Sun, M Jia, H Ren, B Yang, W Chi, G Xin… - Nature …, 2021 - nature.com
A functional mitotic spindle is essential for accurate chromosome congression and
segregation during cell proliferation; however, the underlying mechanisms of its assembly …

[HTML][HTML] GSK3β-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis

B Zhang, T Zhang, G Wang, G Wang, W Chi… - PLoS …, 2015 - journals.plos.org
The primary cilium, which disassembles before mitotic entry and reassembles after mitosis,
organizes many signal transduction pathways that are crucial for cell life and individual …

[HTML][HTML] DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6

X Xu, S Huang, B Zhang, F Huang, W Chi, J Fu… - Nature …, 2017 - nature.com
Centrosome number is tightly controlled during the cell cycle to ensure proper spindle
assembly and cell division. However, the underlying mechanism that controls centrosome …

[HTML][HTML] PLK4-phosphorylated NEDD1 facilitates cartwheel assembly and centriole biogenesis initiations

W Chi, G Wang, G Xin, Q Jiang, C Zhang - Journal of Cell Biology, 2021 - rupress.org
Centrosome duplication occurs under strict spatiotemporal regulation once per cell cycle,
and it begins with cartwheel assembly and daughter centriole biogenesis at the lateral sites …

Sufu negatively regulates both initiations of centrosome duplication and DNA replication

T Zhuang, B Zhang, Y Song, F Huang… - Proceedings of the …, 2021 - National Acad Sciences
Centrosome duplication and DNA replication are two pivotal events that higher eukaryotic
cells use to initiate proliferation. While DNA replication is initiated through origin licensing …