[HTML][HTML] The consequences of refractory epilepsy and its treatment

KD Laxer, E Trinka, LJ Hirsch, F Cendes, J Langfitt… - Epilepsy & behavior, 2014 - Elsevier
Abstract Seizures in some 30% to 40% of patients with epilepsy fail to respond to
antiepileptic drugs or other treatments. While much has been made of the risks of new drug …

Localization of seizure foci: pitfalls and caveats

P Jayakar, M Duchowny, TJ Resnick… - Journal of Clinical …, 1991 - journals.lww.com
The pitfalls and difficulties in accurately localizing seizure foci are reviewed. Basic issues
regarding modeling, volume conduction, inhomogeneities, and corticocortical propagation …

Hemifacial seizures and cerebellar ganglioglioma: an epilepsy syndrome of infancy with seizures of cerebellar origin

AS Harvey, P Jayaka, M Duchowny… - Annals of Neurology …, 1996 - Wiley Online Library
We investigated a 6‐month‐old infant with daily episodes of left hemifacial contraction, head
and eye deviation to the right, nystagmoid jerks to the right, autonomic dysfunction, and …

Different features of histopathological subtypes of pediatric focal cortical dysplasia

P Krsek, B Maton, B Korman… - Annals of Neurology …, 2008 - Wiley Online Library
Objective Focal cortical dysplasia (FCD) is the most frequent pathological finding in pediatric
epilepsy surgery patients. Several histopathological types of FCD are distinguished. The aim …

Epilepsy surgery in children with tuberous sclerosis complex: presurgical evaluation and outcome

S Koh, P Jayakar, C Dunoyer, SE Whiting… - …, 2000 - Wiley Online Library
Purpose: Children with tuberous sclerosis complex (TSC) benefit from excisional surgery if
seizures can be localized to a single tuber. We evaluated the role of noninvasive studies to …

Validation of the quality of life in childhood epilepsy questionnaire in American epilepsy patients

M Sabaz, JA Lawson, DR Cairns, MS Duchowny… - Epilepsy & Behavior, 2003 - Elsevier
The aim of this study was to adapt the Australian Quality of Life in Childhood Epilepsy
Questionnaire (QOLCE) and determine its psychometric properties in a North American …

Epilepsy surgery in patients with normal or nonfocal MRI scans: integrative strategies offer long‐term seizure relief

P Jayakar, C Dunoyer, P Dean, J Ragheb… - …, 2008 - Wiley Online Library
Purpose: Excisional surgery achieves seizure freedom in a large proportion of children with
intractable lesional epilepsy, but the outcome for children without a focal lesion on MRI is …

Language cortex representation: effects of developmental versus acquired pathology

M Duchowny, P Jayakar, AS Harvey… - Annals of Neurology …, 1996 - Wiley Online Library
Relatively little is known about language cortex representation in patients with
developmental pathology and epilepsy. We report the results of mapping language by …

Surgery for epilepsy due to cortical malformations: ten‐year follow‐up

L Hamiwka, P Jayakar, T Resnick, G Morrison… - …, 2005 - Wiley Online Library
Children with malformations of cortical development represent a significant proportion of
pediatric epilepsy surgery candidates. From a cohort of 40 children operated on between …

Medically resistant pediatric insular-opercular/perisylvian epilepsy. Part 2: outcome following resective surgery

AG Weil, NMD Le, P Jayakar, T Resnick, I Miller… - Journal of …, 2016 - thejns.org
OBJECTIVE Seizure onset in the insular cortex as a cause of refractory epilepsy is
underrepresented in the pediatric population, possibly due to difficulties localizing seizure …