Inflammation of the adipose tissue plays an important role in the development of several
chronic diseases associated with obesity. Polyphenols of extra virgin olive oil (EVOO), such …

Aim: Owing to their catalytic properties as reactive oxygen species scavengers, cerium oxide
nanoparticles (nanoceria) have become an extremely promising candidate for medical …

Reactive oxygen species (ROS) are active molecules involved in several biological
functions. When the production of ROS is not counterbalanced by the action of protective …

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a rare early-onset
neurological disease caused by mutations in SACS, which encodes sacsin. The complex …

CLN5 disease is a rare form of late-infantile neuronal ceroid lipofuscinosis (NCL) caused by
mutations in the CLN5 gene that encodes a protein whose primary function and …

CLN5 disease (MIM: 256731) represents a rare late-infantile form of neuronal ceroid
lipofuscinosis (NCL), caused by mutations in the CLN5 gene that encodes the CLN5 protein …

Oxidative phosphorylation (OxPhos) is the basic function of mitochondria, although the
landscape of mitochondrial functions is continuously growing to include more aspects of …

Background: Remarkable deregulation of several microRNAs (miRNAs) is demonstrated in
cutaneous melanoma. hsa-miR-193a-3p is reported to be under-expressed in tissues and in …

Thanks to advances in gene sequencing, RYR1-related myopathy (RYR1-RM) is now
known to manifest itself in vastly heterogeneous forms, whose clinical interpretation is …

Dominant mutations in ubiquitously expressed mitofusin 2 gene (MFN2) cause Charcot-
Marie-Tooth type 2A (CMT2A; OMIM 609260), an inherited sensory-motor neuropathy that …