Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells
N Ertych, A Stolz, A Stenzinger, W Weichert… - Nature cell …, 2014 - nature.com
Chromosomal instability (CIN) is defined as the perpetual missegregation of whole
chromosomes during mitosis and represents a hallmark of human cancer. However, the …
chromosomes during mitosis and represents a hallmark of human cancer. However, the …
Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification
MT Parsons, E Tudini, H Li, E Hahnen… - Human …, 2019 - Wiley Online Library
The multifactorial likelihood analysis method has demonstrated utility for quantitative
assessment of variant pathogenicity for multiple cancer syndrome genes. Independent data …
assessment of variant pathogenicity for multiple cancer syndrome genes. Independent data …
[HTML][HTML] Amygdalin Blocks Bladder Cancer Cell Growth In Vitro by Diminishing Cyclin A and cdk2
J Makarević, J Rutz, E Juengel, S Kaulfuss, M Reiter… - PloS one, 2014 - journals.plos.org
Amygdalin, a natural compound, has been used by many cancer patients as an alternative
approach to treat their illness. However, whether or not this substance truly exerts an anti …
approach to treat their illness. However, whether or not this substance truly exerts an anti …
[HTML][HTML] PIK3CA mutations are specifically localized to lymphatic endothelial cells of lymphatic malformations
H Blesinger, S Kaulfuß, T Aung, S Schwoch, L Prantl… - PLoS …, 2018 - journals.plos.org
Lymphatic malformations (LM) are characterized by the overgrowth of lymphatic vessels
during pre-and postnatal development. Macrocystic, microcystic and combined forms of LM …
during pre-and postnatal development. Macrocystic, microcystic and combined forms of LM …
[HTML][HTML] Germline loss-of-function variants in the BARD1 gene are associated with early-onset familial breast cancer but not ovarian cancer
N Weber-Lassalle, J Borde, K Weber-Lassalle… - Breast Cancer …, 2019 - Springer
Background The role of the BARD1 gene in breast cancer (BC) and ovarian cancer (OC)
predisposition remains elusive, as published case-control investigations have revealed …
predisposition remains elusive, as published case-control investigations have revealed …
The relevance of estrogen receptor-β expression to the antiproliferative effects observed with histone deacetylase inhibitors and phytoestrogens in prostate cancer …
M Stettner, S Kaulfuß, P Burfeind, S Schweyer… - Molecular Cancer …, 2007 - AACR
In the prostate, estrogen receptor β (ERβ), the preferred receptor for phytoestrogens, has
features of a tumor suppressor. To investigate the mechanisms underlying the beneficial …
features of a tumor suppressor. To investigate the mechanisms underlying the beneficial …
Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a,-224,-132 and let7g
Background and purpose Preoperative chemoradiotherapy (CRT) represents the standard
treatment for locally advanced rectal cancer. Tumor response and progression vary …
treatment for locally advanced rectal cancer. Tumor response and progression vary …
The detection of isochromosome i (12p) in malignant germ cell tumours and tumours with somatic malignant transformation by the use of quantitative real‐time …
A Fichtner, A Richter, S Filmar, NT Gaisa… - …, 2021 - Wiley Online Library
Aims Malignant germ cell tumours (GCTs) of the testis are rare neoplasms, but the most
common solid malignancies in young men. World Health Organization guidelines divide …
common solid malignancies in young men. World Health Organization guidelines divide …
[HTML][HTML] Amygdalin Influences Bladder Cancer Cell Adhesion and Invasion In Vitro
J Makarević, J Rutz, E Juengel, S Kaulfuss, I Tsaur… - PloS one, 2014 - journals.plos.org
The cyanogenic diglucoside amygdalin, derived from Rosaceae kernels, is employed by
many patients as an alternative anti-cancer treatment. However, whether amygdalin indeed …
many patients as an alternative anti-cancer treatment. However, whether amygdalin indeed …
Expression and functional analysis of Bax inhibitor‐1 in human breast cancer cells
M Grzmil, S Kaulfuss, P Thelen… - The Journal of …, 2006 - Wiley Online Library
Recently, deregulated expression of the anti‐apoptotic protein Bax inhibitor‐1 (BI‐1) has
been shown in several human cancers. In this report, we show that BI‐1 is expressed at …
been shown in several human cancers. In this report, we show that BI‐1 is expressed at …