Abstract Objective Malays comprise an Asian cultural group reported to have low breast
cancer screening uptake rates and poor cancer outcomes. Little is known about Malay …

Associations of sarcoma with inherited cancer syndromes implicate genetic predisposition in
sarcoma development. However, due to the apparently sporadic nature of sarcomas, little …

PURPOSE Genetic testing has clinical utility in the management of patients with hereditary
cancer syndromes. However, the increased likelihood of encountering a variant of uncertain …

Cascade testing for cancer predisposition offers a highly efficient and cost-effective method
for identifying individuals at increased risk for cancer, in whom targeted interventions can …

Objective Somatic POLE mutations have been found in a subset of endometrioid ECs
particularly in FIGO grade 3 tumors while POLD1 mutations are reportedly rare in ECs. While …

Background Fabry disease is an X-linked inherited lysosomal storage disease that can be
treated with the enzymes of agalsidase beta (Fabrazyme) and agalsidase alfa (Replagal) …

The increase in demand for clinical cancer genetics services has impacted the ability to
provide services timeously. Given limited resources, this often results in extended …

Device quantization of in-memory computing (IMC) that considers the non-negligible
variation and finite dynamic range of practical memory technology is investigated, aiming for …

Purpose Previous reports cite high costs of clinical cancer genetic testing as main barriers to
patient's willingness to test. We report findings of a pilot study that evaluates how different …

Objective Reluctance to share hereditary cancer syndrome genetic test results with family is
reported among Asian patients. This study aims to explore patient factors influencing result …