Introduction: Vestibular schwannomas (VS) account for approximately 85% of tumors in the
cerebello-pontine angle, with a lifetime incidence of approximately 1 in 1000. Most are …

Aims/Purpose: Spheno-orbital meningiomas account for 9% of all adult intracranial
meningiomas. Complete resection is extremely difficult with this condition. We report on our …

Objectives Schwannomatosis is a dominantly inherited condition predisposing to
schwannomas of mainly spinal and peripheral nerves with some diagnostic overlap with …

Objective: To determine the specificity of the current clinical diagnostic criteria for
neurofibromatosis type 2 (NF2) relative to the requirement for unilateral vestibular …

Background Meningiomas have been reported to occur in approximately 50% of
neurofibromatosis type 2 (NF2) patients. The NF2 gene is commonly biallelically inactivated …

Purpose To evaluate the incidence of mosaicism in de novo neurofibromatosis 2 (NF2).
Methods Patients fulfilling NF2 criteria, but with no known affected family member from a …

Background Inflammation is hypothesized to be a key event in the growth of sporadic
vestibular schwannoma (VS). In this study we sought to investigate the relationship between …

Importance Meningiomas and schwannomas are usually sporadic, isolated tumors occurring
in adults older than 60 years and are rare in children and young adults. Multiple …

Purpose We have evaluated deficiencies in existing diagnostic criteria for neurofibromatosis
2 (NF2). Methods Two large databases of individuals fulfilling NF2 criteria (n= 1361) and …

NF2-schwannomatosis is the most common genetic predisposition syndrome associated
with meningioma. Meningioma in NF2-schwannomatosis is a major source of morbidity and …