Background Family history is a significant risk factor for prostate cancer, although the
molecular basis for this association is poorly understood. Linkage studies have implicated …

Background Single-nucleotide polymorphisms (SNPs) in five chromosomal regions—three
at 8q24 and one each at 17q12 and 17q24. 3—have been associated with prostate cancer …

Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify …

We conducted a genome-wide SNP association study on prostate cancer on over 23,000
Icelanders, followed by a replication study including over 15,500 individuals from Europe …

Deletions on human chromosome 8p22–23 in prostate cancer cells 1 and linkage studies in
families affected with hereditary prostate cancer (HPC) 2, 3, 4 have implicated this region in …

Background Germline mutations in BRCA1/2 and ATM have been associated with prostate
cancer (PCa) risk. Objective To directly assess whether germline mutations in these three …

To identify genetic susceptibility loci for hepatitis B virus (HBV)-related hepatocellular
carcinoma (HCC) in the Chinese population, we carried out a genome-wide association …

In search of common risk alleles for prostate cancer that could contribute to high rates of the
disease in men of African ancestry, we conducted a genome-wide association study, with …

Most men diagnosed with prostate cancer will experience indolent disease; hence,
discovering genetic variants that distinguish aggressive from nonaggressive prostate cancer …

We report a genome-wide association study in 10,286 cases and 9,135 controls of
European ancestry in the Cancer Genetic Markers of Susceptibility (CGEMS) initiative. We …