User profiles for "author:S Deutsch"

Stephen I. Deutsch

- Verified email at evms.edu - Cited by 8835

Samuel Deutsch

- Verified email at nutcrackerx.com - Cited by 8622

Chromosome 21 and down syndrome: from genomics to pathophysiology

…, R Lyle, ET Dermitzakis, A Reymond, S Deutsch - Nature reviews …, 2004 - nature.com
The sequence of chromosome 21 was a turning point for the understanding of Down
syndrome. Comparative genomics is beginning to identify the functional components of the …

New insights into physiology and metabolism of Propionibacterium freudenreichii

A Thierry, SM Deutsch, H Falentin, M Dalmasso… - International journal of …, 2011 - Elsevier
Dairy propionibacteria are Actinobacteria, mainly isolated from dairy environments.
Propionibacterium freudenreichii has been used for a long time as a ripening culture in …

A “glutamatergic hypothesis” of schizophrenia: rationale for pharmacotherapy with glycine

SI Deutsch, J Mastropaolo, BL Schwartz… - Clinical …, 1989 - journals.lww.com
Pharmacological interference with glutamatergic transmission at the level of the N-methyl-D-
aspartate (NMDA) receptor complex in humans can precipitate a psychosis strikingly similar …

Common regulatory variation impacts gene expression in a cell type–dependent manner

AS Dimas, S Deutsch, BE Stranger, SB Montgomery… - Science, 2009 - science.org
Studies correlating genetic variation to gene expression facilitate the interpretation of
common human phenotypes and disease. As functional variants may be operating in a …

Organizational effectiveness: A multiple-constituency approach

T Connolly, EJ Conlon, SJ Deutsch - Academy of management …, 1980 - journals.aom.org
Current approaches to organizational effectiveness are conceptually conflicting and
empirically arid. They appear handicapped by a desire to produce a single effectiveness …

[HTML][HTML] Genome-wide associations of gene expression variation in humans

…, MS Forrest, AG Clark, MJ Minichiello, S Deutsch… - PLoS …, 2005 - journals.plos.org
The exploration of quantitative variation in human populations has become one of the major
priorities for medical genetics. The successful identification of variants that contribute to …

[PDF][PDF] Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3′ untranslated region: a mechanism for functional …

…, C Borel, M Gagnebin, GR Grant, S Deutsch… - The American Journal of …, 2007 - cell.com
Animal microRNAs (miRNAs) regulate gene expression through base pairing to their targets
within the 3′ untranslated region (UTR) of protein-coding genes. Single-nucleotide …

[HTML][HTML] Genetic structure of Europeans: a view from the North–East

…, S Marsal, A Julią, SE Antonarakis, S Deutsch… - PloS one, 2009 - journals.plos.org
Using principal component (PC) analysis, we studied the genetic constitution of 3,112
individuals from Europe as portrayed by more than 270,000 single nucleotide …

Size-dependent catalytic activity of supported metal clusters

Z Xu, FS Xiao, SK Purnell, O Alexeev, S Kawi… - Nature, 1994 - nature.com
BECAUSE catalysis by metals is a surface phenomenon, many technological catalysts
contain small (typically nanometre-sized) supported metal particles with a large fraction of …

Methane yield phenotypes linked to differential gene expression in the sheep rumen microbiome

…, J Froula, S Kittelmann, C Fan, S Deutsch… - Genome …, 2014 - genome.cshlp.org
Ruminant livestock represent the single largest anthropogenic source of the potent
greenhouse gas methane, which is generated by methanogenic archaea residing in …