Chromosome 21 and down syndrome: from genomics to pathophysiology
The sequence of chromosome 21 was a turning point for the understanding of Down
syndrome. Comparative genomics is beginning to identify the functional components of the …
syndrome. Comparative genomics is beginning to identify the functional components of the …
New insights into physiology and metabolism of Propionibacterium freudenreichii
A Thierry, SM Deutsch, H Falentin, M Dalmasso… - International journal of …, 2011 - Elsevier
Dairy propionibacteria are Actinobacteria, mainly isolated from dairy environments.
Propionibacterium freudenreichii has been used for a long time as a ripening culture in …
Propionibacterium freudenreichii has been used for a long time as a ripening culture in …
A “glutamatergic hypothesis” of schizophrenia: rationale for pharmacotherapy with glycine
SI Deutsch, J Mastropaolo, BL Schwartz… - Clinical …, 1989 - journals.lww.com
Pharmacological interference with glutamatergic transmission at the level of the N-methyl-D-
aspartate (NMDA) receptor complex in humans can precipitate a psychosis strikingly similar …
aspartate (NMDA) receptor complex in humans can precipitate a psychosis strikingly similar …
Common regulatory variation impacts gene expression in a cell type–dependent manner
Studies correlating genetic variation to gene expression facilitate the interpretation of
common human phenotypes and disease. As functional variants may be operating in a …
common human phenotypes and disease. As functional variants may be operating in a …
Organizational effectiveness: A multiple-constituency approach
T Connolly, EJ Conlon, SJ Deutsch - Academy of management …, 1980 - journals.aom.org
Current approaches to organizational effectiveness are conceptually conflicting and
empirically arid. They appear handicapped by a desire to produce a single effectiveness …
empirically arid. They appear handicapped by a desire to produce a single effectiveness …
[HTML][HTML] Genome-wide associations of gene expression variation in humans
The exploration of quantitative variation in human populations has become one of the major
priorities for medical genetics. The successful identification of variants that contribute to …
priorities for medical genetics. The successful identification of variants that contribute to …
[PDF][PDF] Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3′ untranslated region: a mechanism for functional …
Animal microRNAs (miRNAs) regulate gene expression through base pairing to their targets
within the 3′ untranslated region (UTR) of protein-coding genes. Single-nucleotide …
within the 3′ untranslated region (UTR) of protein-coding genes. Single-nucleotide …
[HTML][HTML] Genetic structure of Europeans: a view from the North–East
Using principal component (PC) analysis, we studied the genetic constitution of 3,112
individuals from Europe as portrayed by more than 270,000 single nucleotide …
individuals from Europe as portrayed by more than 270,000 single nucleotide …
Size-dependent catalytic activity of supported metal clusters
Z Xu, FS Xiao, SK Purnell, O Alexeev, S Kawi… - Nature, 1994 - nature.com
BECAUSE catalysis by metals is a surface phenomenon, many technological catalysts
contain small (typically nanometre-sized) supported metal particles with a large fraction of …
contain small (typically nanometre-sized) supported metal particles with a large fraction of …
Methane yield phenotypes linked to differential gene expression in the sheep rumen microbiome
…, J Froula, S Kittelmann, C Fan, S Deutsch… - Genome …, 2014 - genome.cshlp.org
Ruminant livestock represent the single largest anthropogenic source of the potent
greenhouse gas methane, which is generated by methanogenic archaea residing in …
greenhouse gas methane, which is generated by methanogenic archaea residing in …