Histopathological diagnosis of partial and complete hydatidiform mole in the first trimester of pregnancy
NJ Sebire, RA Fisher, HC Rees - Pediatric and developmental pathology, 2003 - Springer
The diagnosis of molar pregnancy is a continuing diagnostic problem for many practicing
histopathologists who are required to examine specimens of products of conception …
histopathologists who are required to examine specimens of products of conception …
[PDF][PDF] Familial recurrent hydatidiform mole
RA Fisher, MD Hodges, ES Newlands - a review, 2004 - researchgate.net
For appropriate management of molar pregnancies it is important to identify those women
who have familial recurrent HM. having no fetus except in the rare case of a CHM with …
who have familial recurrent HM. having no fetus except in the rare case of a CHM with …
Genetics of gestational trophoblastic disease
RA Fisher, GJ Maher - Best Practice & Research Clinical Obstetrics & …, 2021 - Elsevier
The abnormal pregnancies complete and partial hydatidiform mole are genetically unusual,
being associated with two copies of the paternal genome. Typical complete hydatidiform …
being associated with two copies of the paternal genome. Typical complete hydatidiform …
Choriocarcinoma and partial hydatidiform moles
MJ Seckl, RA Fisher, G Salerno, H Rees, FJ Paradinas… - The Lancet, 2000 - thelancet.com
Summary Background Partial hydatidiform moles (PMs) rarely require chemotherapy and
have never previously been proven to transform into choriocarcinoma, the most malignant …
have never previously been proven to transform into choriocarcinoma, the most malignant …
Outcome of twin pregnancies with complete hydatidiform mole and healthy co-twin
NJ Sebire, M Foskett, FJ Paradinas, RA Fisher… - The Lancet, 2002 - thelancet.com
We assessed 77 twin pregnancies, comprising complete hydatidiform mole (CHM) and
healthy co-twin, to ascertain the risks to the mother and baby of continuing the pregnancy …
healthy co-twin, to ascertain the risks to the mother and baby of continuing the pregnancy …
Prognostic markers and long-term outcome of placental-site trophoblastic tumours: a retrospective observational study
Background Placental-site trophoblastic tumours are a rare form of gestational trophoblastic
disease and consequently information about optimum management or prognostic factors is …
disease and consequently information about optimum management or prognostic factors is …
[PDF][PDF] Mutations causing familial biparental hydatidiform mole implicate c6orf221 as a possible regulator of genomic imprinting in the human oocyte
DA Parry, CV Logan, BE Hayward, M Shires… - The American Journal of …, 2011 - cell.com
Familial biparental hydatidiform mole (FBHM) is the only known pure maternal-effect
recessive inherited disorder in humans. Affected women, although developmentally normal …
recessive inherited disorder in humans. Affected women, although developmentally normal …
[PDF][PDF] EMA/CO for high-risk gestational trophoblastic neoplasia: good outcomes with induction low-dose etoposide-cisplatin and genetic analysis
C Alifrangis, R Agarwal, D Short… - Journal of clinical …, 2013 - researchgate.net
Purpose Patients with high-risk (International Federation of Gynecology and Obstetrics score
7) gestational trophoblastic neoplasia (GTN) frequently receive etoposide, methotrexate …
7) gestational trophoblastic neoplasia (GTN) frequently receive etoposide, methotrexate …
Discrimination of complete hydatidiform mole from its mimics by immunohistochemistry of the paternally imprinted gene product p57 KIP2
DH Castrillon, D Sun, S Weremowicz… - The American journal …, 2001 - journals.lww.com
The p57 KIP2 protein is a cell cycle inhibitor and tumor suppressor encoded by a strongly
paternally imprinted gene. We explored the utility of p57 KIP2 as a diagnostic marker in …
paternally imprinted gene. We explored the utility of p57 KIP2 as a diagnostic marker in …
Pembrolizumab is effective for drug-resistant gestational trophoblastic neoplasia
Gestational trophoblastic disease represents a spectrum of pregnancy related disorders,
ranging from pre-malignant hydatidiform mole to malignant tumours, collectively referred to …
ranging from pre-malignant hydatidiform mole to malignant tumours, collectively referred to …