Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis
Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but
accumulating evidence indicates that inflammation has a critical role in its pathogenesis …
accumulating evidence indicates that inflammation has a critical role in its pathogenesis …
Functional profiling of the Saccharomyces cerevisiae genome
Determining the effect of gene deletion is a fundamental approach to understanding gene
function. Conventional genetic screens exhibit biases, and genes contributing to a …
function. Conventional genetic screens exhibit biases, and genes contributing to a …
[HTML][HTML] Opportunities and challenges associated with clinical diagnostic genome sequencing: a report of the Association for Molecular Pathology
This report of the Whole Genome Analysis group of the Association for Molecular Pathology
illuminates the opportunities and challenges associated with clinical diagnostic genome …
illuminates the opportunities and challenges associated with clinical diagnostic genome …
[HTML][HTML] Hereditary hemorrhagic telangiectasia: an overview of diagnosis and management in the molecular era for clinicians
P Bayrak-Toydemir, R Mao, S Lewin, J McDonald - Genetics in Medicine, 2004 - Elsevier
Abstract Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome) is a
relatively common, underdiagnosed autosomal-dominant disorder of arteriovenous …
relatively common, underdiagnosed autosomal-dominant disorder of arteriovenous …
[HTML][HTML] New-onset IgG autoantibodies in hospitalized patients with COVID-19
SE Chang, A Feng, W Meng, SA Apostolidis… - Nature …, 2021 - nature.com
COVID-19 is associated with a wide range of clinical manifestations, including autoimmune
features and autoantibody production. Here we develop three protein arrays to measure IgG …
features and autoantibody production. Here we develop three protein arrays to measure IgG …
HIV/STD risk behaviors and perceptions among rural-to-urban migrants in China
X Li, X Fang, D Lin, R Mao, J Wang… - AIDS Education and …, 2004 - Guilford Press
Data from 2,153 sexually active rural-to-urban migrants in China were analyzed to examine
the relationship between the movement of rural-to-urban migration and increased HIV/STD …
the relationship between the movement of rural-to-urban migration and increased HIV/STD …
[HTML][HTML] Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia
V Lukacs, J Mathur, R Mao, P Bayrak-Toydemir… - Nature …, 2015 - nature.com
Piezo1 ion channels are mediators of mechanotransduction in several cell types including
the vascular endothelium, renal tubular cells and erythrocytes. Gain-of-function mutations in …
the vascular endothelium, renal tubular cells and erythrocytes. Gain-of-function mutations in …
A fourth locus for hereditary hemorrhagic telangiectasia maps to chromosome 7
P Bayrak‐Toydemir, J McDonald… - American journal of …, 2006 - Wiley Online Library
Hereditary hemorrhagic telangiectasia (HHT) is a genetically and clinically heterogeneous
multisystem vascular dysplasia. Mutations of the endoglin and ACVRL1 genes are known to …
multisystem vascular dysplasia. Mutations of the endoglin and ACVRL1 genes are known to …
Global up-regulation of chromosome 21 gene expression in the developing Down syndrome brain
R Mao, CL Zielke, HR Zielke, J Pevsner - Genomics, 2003 - Elsevier
Down syndrome (DS) results from complete or partial triplication of human chromosome 21.
It is assumed that the neurological and other symptoms are caused by the overexpression of …
It is assumed that the neurological and other symptoms are caused by the overexpression of …
Genotype–phenotype correlation in hereditary hemorrhagic telangiectasia: mutations and manifestations
P Bayrak‐Toydemir, J McDonald… - American journal of …, 2006 - Wiley Online Library
Hereditary hemorrhagic telangiectasia (HHT) is a genetically heterogeneous vascular
dysplasia with multiple telangiectases and arteriovenous malformations and it is caused by …
dysplasia with multiple telangiectases and arteriovenous malformations and it is caused by …