Background Oliver–McFarlane syndrome is characterised by trichomegaly, congenital
hypopituitarism and retinal degeneration with choroidal atrophy. Laurence–Moon syndrome …

Purpose To report an anatomic change following subretinal injection of voretigene
neparvovec-rzyl (VN) for RPE65-mediated Leber congenital amaurosis. Design Multicenter …

Human X-linked blue-cone monochromacy (BCM), a disabling congenital visual disorder of
cone photoreceptors, is a candidate disease for gene augmentation therapy. BCM is caused …

PURPOSE: To determine visual and anatomic outcomes for patients with persistent fetal
vasculature (PFV) observed or treated with surgery. DESIGN: Retrospective interventional …

Background Leber congenital amaurosis (LCA) is a congenital retinal dystrophy that results
in significant and often severe vision loss at an early age. Comprehensive analysis of the …

Nanophthalmos is a rare, potentially devastating eye condition characterized by small eyes
with relatively normal anatomy, a high hyperopic refractive error, and frequent association …

Purpose The purpose of this study was to evaluate intravitreal methotrexate infusion (IMI)
during pars plana vitrectomy (PPV) for retinal detachment in patients with high risk for the …

Background To evaluate the safety and visual outcomes of combined phacoemulsification
and sutureless 23-gauge vitrectomy for concomitant cataract and vitreoretinal diseases …

Objective To explore the effect of patients' age, baseline visual acuity (VA), and
intraoperative foveal detachment on outcomes of subretinal voretigene neparvovec-rzyl …

Purpose To determine the feasibility and safety of bilateral simultaneous vitreoretinal
surgery in pediatric patients. Design International, multicenter, interventional, retrospective …