Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers

RS van der Post, IP Vogelaar, F Carneiro… - Journal of medical …, 2015 - jmg.bmj.com
Germline CDH1 mutations confer a high lifetime risk of developing diffuse gastric (DGC) and
lobular breast cancer (LBC). A multidisciplinary workshop was organised to discuss genetic …

Hereditary diffuse gastric cancer: updated clinical practice guidelines

VR Blair, M McLeod, F Carneiro, DG Coit… - The Lancet …, 2020 - thelancet.com
Hereditary diffuse gastric cancer (HDGC) is an autosomal dominant cancer syndrome that is
characterised by a high prevalence of diffuse gastric cancer and lobular breast cancer. It is …

Acceptability and accuracy of a non-endoscopic screening test for Barrett's oesophagus in primary care: cohort study

SR Kadri, P Lao-Sirieix, M O'Donovan, I Debiram… - Bmj, 2010 - bmj.com
Objectives To determine the accuracy and acceptability to patients of non-endoscopic
screening for Barrett's oesophagus, using an ingestible oesophageal sampling device …

[PDF][PDF] Important role of the GLP-1 axis for glucose homeostasis after bariatric surgery

P Larraufie, GP Roberts, AK McGavigan, RG Kay, J Li… - Cell reports, 2019 - cell.com
Bariatric surgery is widely used to treat obesity and improves type 2 diabetes beyond
expectations from the degree of weight loss. Elevated post-prandial concentrations of …

A 4-gene signature predicts survival of patients with resected adenocarcinoma of the esophagus, junction, and gastric cardia

CJ Peters, JRE Rees, RH Hardwick, JS Hardwick… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: The incidence of esophageal and junctional adenocarcinoma has
increased 6-fold in the past 30 years and 5-year survival remains approximately 20 …

Comparison of human and murine enteroendocrine cells by transcriptomic and peptidomic profiling

GP Roberts, P Larraufie, P Richards, RG Kay… - Diabetes, 2019 - Am Diabetes Assoc
Enteroendocrine cells (EECs) produce hormones such as glucagon-like peptide 1 and
peptide YY that regulate food absorption, insulin secretion, and appetite. Based on the …

[HTML][HTML] Comparative study of endoscopic surveillance in hereditary diffuse gastric cancer according to CDH1 mutation status

EZ Mi, EZ Mi, M di Pietro, M O'Donovan… - Gastrointestinal …, 2018 - Elsevier
Background and Aims Hereditary diffuse gastric cancer (HDGC) accounts for 1% of gastric
cancer cases. For patients with a germline CDH1 mutation, risk-reducing gastrectomy is …

[HTML][HTML] Incidence and survival of oesophageal and gastric cancer in England between 1998 and 2007, a population-based study

VH Coupland, W Allum, JM Blazeby, MA Mendall… - BMC cancer, 2012 - Springer
Background Major changes in the incidence of oesophageal and gastric cancers have been
reported internationally. This study describes recent trends in incidence and survival of …

Prospective cohort study assessing outcomes of patients from families fulfilling criteria for hereditary diffuse gastric cancer undergoing endoscopic surveillance

YC Lim, M di Pietro, M O'Donovan, S Richardson… - Gastrointestinal …, 2014 - Elsevier
Background Prophylactic total gastrectomy is performed in hereditary diffuse gastric cancer
(HDGC) patients carrying the CDH1 mutation because endoscopic surveillance often fails to …

[HTML][HTML] Preclinical evaluation of the versius surgical system, a new robot-assisted surgical device for use in minimal access general and colorectal procedures

J Morton, RH Hardwick, HS Tilney, AM Gudgeon… - Surgical …, 2021 - Springer
Objective To evaluate the utility of a new robot-assisted surgical system (the Versius
Surgical System, CMR Surgical, Cambridge, UK) for use in minimal access general and …