Amyotrophic lateral sclerosis (ALS) is an incurable degenerative disorder of motoneurons.
We recently reported that reduced expression of Vegfa causes ALS-like motoneuron …

Objective This meta-analysis attempted to derive pooled estimates for the associations
between various cardiovascular-renal disorders and the deletion/insertion (D/I) …

Multiple births after artificial induction of ovulation (AIO) are usually considered to be due to
fertilisation of multiple ova. In the East Flanders Prospective Twin Study between 1978 and …

OBJECTIVES: Correct diagnosis of inflammatory bowel disease (IBD), especially the
differentiation between Crohn's disease (CD) and ulcerative colitis (UC), is highly important …

Background Variants of the human genes coding for renin, angiotensin-converting enzyme
(ACE), angiotensinogen (AGT) and the angiotensin II type-I receptor (AT1R) are …

The human gastrointestinal (GI) tract microbiota acts like a virtual organ and is suggested to
be of great importance in human energy balance and weight control. This study included 40 …

* Center for Gastrointestinal Research, University of Leuven, Leuven;‡ University Center for
Statistics, Leuven; and § Center for Human Genetics, Leuven, Belgium (questionnaire …

Background Evidence that a deficient innate immune response toward the bacterial flora of
the gut plays a role in the pathogenesis of inflammatory bowel disease (IBD) is growing. This …

Many genetic disorders demonstrate mutations that can be traced to a founder, sometimes a
person who can be identified. These founder mutations have generated considerable …

Background: Both genetic and environmental factors are known to affect body mass index
(BMI), but detailed understanding of how their effects differ during childhood and …