The transcriptomics field has developed rapidly with the advent of next-generation
sequencing technologies. RNA-seq has now displaced microarrays as the preferred method …

The Clustal W and Clustal X multiple sequence alignment programs have been completely
rewritten in C++. This will facilitate the further development of the alignment algorithms in the …

Background Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the
two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic …

Gonadal sex differentiation proceeds by the interplay of various genes including the
transcription factors and secretory factors in a complex network. The sex-differentiating …

Background The derivation of domestic cattle from the extinct wild aurochs (Bos primigenius)
has been well-documented by archaeological and genetic studies. Genetic studies point …

The aims of this study were to 1) identify the earliest transcriptional response of the bovine
endometrium to the presence of the conceptus (using RNAseq), 2) investigate if these genes …

Diabetic nephropathy is currently the leading cause of end-stage renal disease worldwide,
and occurs in approximately one third of all diabetic patients. The molecular pathogenesis of …

Successful establishment and maintenance of pregnancy can be attained only through
optimum conceptus-maternal cross talk. Despite significant progress in our understanding of …

Successful growth and development of the posthatching blastocyst and pregnancy
establishment are a result of the interaction between a competent embryo and a receptive …

Infantile hepatopathies are life-threatening liver disorders that manifest in the first few
months of life. We report on a consanguineous Irish Traveller family that includes six …