Speed-accuracy trade-off is an intensively studied law governing almost all behavioral tasks
across species. Here we show that motivation by reward breaks this law, by simultaneously …

Background Heterozygous loss‐of‐function mutations in the acid beta‐glucocerebrosidase
(GBA1) gene, responsible for the recessive lysosomal storage disorder, Gaucher's disease …

Primary torsion dystonia (PTD) is a clinically and genetically heterogeneous movement
disorder. DYT1 on chromosome 9q34 was the first PTD gene to be mapped. A 3-bp (GAG) …

Paroxysmal kinesigenic dyskinesia (PKD) is characterised by paroxysms of choreic,
dystonic, ballistic, or athetoid movements. The attacks typically last seconds to minutes in …

A patient in whom chylothorax was the presenting feature of sarcoidosis is reported.
Mediastinal lymphadenopathy was shown by computed tomographic scanning. Obstruction …

OBJECTIVES to investigate the hypothesis that GTP cyclohydrolase I (GCH1) mutations are
responsible for the phenotype of highly anticholinergic responsive dystonia in patients with …

Disentangling Parkinson's disease (PD) and progressive supranuclear palsy (PSP) may be
a diagnostic challenge. Cognitive signs may be useful, but existing screens are often …

Hyperkalaemia is associated with diabetes, but there are no recent reports of its prevalence
and associations. Serum potassium concentrations were measured in all 1764 patients …

Hereditary geniospasm is an unusual movement disorder causing episodes of involuntary
tremor of the chin and the lower lip. Episodes typically start in early childhood and may be …

Genetic disorders of the central nervous system have a propensity to cause movement disor-
ders or ataxia, as a part of the phenotype, or sometimes as the main phenotypic …