Abstract The Karakoram/Kohistan/India collision zone provides a rare opportunity to study
the roles of subduction and tectonic accretion in crustal growth processes. Magmatic …

Purpose Cisplatin is a chemotherapeutic agent not used routinely for breast cancer
treatment. As a DNA cross-linking agent, cisplatin may be effective treatment for hereditary …

Abstract Learning Objectives After completing this course, the reader will be able to: Discuss
the characteristics of the IGF system including its endocrine as well as tissue growth factor …

Tamoxifen significantly reduces tumor recurrence in certain patients with early-stage
estrogen receptor-positive breast cancer, but markers predictive of treatment failure have not …

Abstract Purpose: BRCA1/2-mutated and some sporadic triple-negative breast cancers
(TNBC) have DNA repair defects and are sensitive to DNA-damaging therapeutics …

DNA repair competency is one determinant of sensitivity to certain chemotherapy drugs,
such as cisplatin. Cancer cells with intact DNA repair can avoid the accumulation of genome …

Purpose The identification of patients with metastatic triple-negative breast cancer (mTNBC)
who are expected to benefit from platinum-based chemotherapy is of interest. We conducted …

PAST - PAlaeontological STatistics, ver. 1.34 Page 1 PAST - PAlaeontological STatistics, ver.
1.34 Øyvind Hammer, DAT Harper and PD Ryan March 17, 2005 1 Introduction Welcome to …

Purpose: Trastuzumab-based therapy improves survival for women with human epidermal
growth factor receptor 2 (HER2)–positive advanced breast cancer. We conducted a …

Purpose: To assess pathologic complete response (pCR), clinical response, feasibility,
safety, and potential predictors of response to preoperative trastuzumab plus vinorelbine in …