User profiles for "author:Norio Sakai"

Norio Sakai

Department of Molecular and Pharmacological Neuroscience, iroshima University
Verified email at hiroshima-u.ac.jp
Cited by 5267

Acyl Fluorides in Late‐Transition‐Metal Catalysis

Y Ogiwara, N Sakai - Angewandte Chemie International Edition, 2020 - Wiley Online Library
In this Review, we summarize the current state of the art in late‐transition‐metal‐catalyzed
reactions of acyl fluorides, covering both their synthesis and further transformations. In …

Distribution of persistent organochlorines in the oceanic air and surface seawater and the role of ocean on their global transport and fate

H Iwata, S Tanabe, N Sakai… - Environmental Science & …, 1993 - ACS Publications
During the last decade, many investigations have been conducted to make clear the global
distribution of per-sistent organochlorinessuch as polychlorinated biphenyls (PCBs) and …

Geographical distribution of persistent organochlorines in air, water and sediments from Asia and Oceania, and their implications for global redistribution from lower …

H Iwata, S Tanabe, N Sakai, A Nishimura… - Environmental …, 1994 - Elsevier
Persistent organochlorines in air, river water and sediment samples were analysed from
eastern and southern Asia (India, Thailand, Vietnam, Malaysia, Indonesia) and Oceania …

Oral pharmacological chaperone migalastat compared with enzyme replacement therapy in Fabry disease: 18-month results from the randomised phase III ATTRACT …

DA Hughes, K Nicholls, SP Shankar… - Journal of medical …, 2017 - jmg.bmj.com
Background Fabry disease is an X-linked lysosomal storage disorder caused by GLA
mutations, resulting in α-galactosidase (α-Gal) deficiency and accumulation of lysosomal …

Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion

H Vega, Q Waisfisz, M Gordillo, N Sakai, I Yanagihara… - Nature …, 2005 - nature.com
Roberts syndrome is an autosomal recessive disorder characterized by craniofacial
anomalies, tetraphocomelia and loss of cohesion at heterochromatic regions of centromeres …

Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect

SS Newton, J Thome, TL Wallace… - Journal of …, 2002 - Soc Neuroscience
The cAMP response element-binding protein (CREB) is a critical integrator of neural
plasticity that is responsive in a brain region-specific manner to a variety of environmental …

Pax1 and Pax9 synergistically regulate vertebral column development

H Peters, B Wilm, N Sakai, K Imai, R Maas… - …, 1999 - journals.biologists.com
The paralogous genes Pax1 and Pax9 constitute one group within the vertebrate Pax gene
family. They encode closely related transcription factors and are expressed in similar …

Microglial α7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role

T Suzuki, I Hide, A Matsubara, C Hama… - Journal of …, 2006 - Wiley Online Library
Microglia perform both neuroprotective and neurotoxic functions in the brain, with this
depending on their state of activation and their release of mediators. Upon P2X7 receptor …

InBr3-Promoted Divergent Approach to Polysubstituted Indoles and Quinolines from 2-Ethynylanilines: Switch from an Intramolecular Cyclization to an Intermolecular …

N Sakai, K Annaka, A Fujita, A Sato… - The Journal of Organic …, 2008 - ACS Publications
Use of a 2-ethynylaniline having an alkyl or aryl group on the terminal alkyne selectively
produced a variety of polyfunctionalized indole derivatives in moderate to excellent yields …

BDNF, NT-3, and NGF released from transplanted neural progenitor cells promote corticospinal axon growth in organotypic cocultures

N Kamei, N Tanaka, Y Oishi, T Hamasaki, K Nakanishi… - Spine, 2007 - journals.lww.com
Study Design. Experimental study of spinal cord injury using an organotypic slice culture.
Objective. To clarify the mechanism of corticospinal axon regeneration following …