Chronic hypertension and adverse pregnancy outcome: a cohort study

AM Panaitescu, A Syngelaki, N Prodan… - … in Obstetrics & …, 2017 - Wiley Online Library
Objective To examine the association between chronic hypertension (CH) and a wide range
of adverse pregnancy outcomes after adjustment for confounding factors in obstetric history …

Bi-allelic loss-of-function variants in KIF21A cause severe fetal akinesia with arthrogryposis multiplex

RJ Falb, AJ Müller, W Klein, M Grimmel… - Journal of medical …, 2023 - jmg.bmj.com
Background Fetal akinesia (FA) results in variable clinical presentations and has been
associated with more than 166 different disease loci. However, the underlying molecular …

Screening for pre‐eclampsia using sFlt‐1/PlGF ratio cut‐off of 38 at 30–37 weeks' gestation

I Dragan, T Georgiou, N Prodan… - … in obstetrics & …, 2017 - Wiley Online Library
Objective To evaluate a soluble fms‐like tyrosine kinase‐1 (sFlt‐1) to placental growth factor
(PlGF) ratio cut‐off of 38 for the prediction of pre‐eclampsia (PE) in routine assessment in …

First trimester screening for common trisomies and microdeletion 22q11. 2 syndrome using cell-free DNA: a prospective clinical study

KO Kagan, M Hoopmann, T Pfaff, N Prodan… - Fetal diagnosis and …, 2020 - karger.com
Objectives: The aims of the study were to assess the false-positive and uninformative test
rate with first trimester cell-free DNA (cfDNA) screening for common trisomies and …

[HTML][HTML] Measurement of the uterocervical angle for the prediction of preterm birth in symptomatic women

P Wagner, J Schlechtendahl, M Hoopmann… - Archives of Gynecology …, 2021 - Springer
Purpose To examine if the uterocervical angle (UCA) can be used to predict preterm delivery
in women with painful and regular uterine contractions and a cervical length of 25 mm or …

Universal cell free DNA or contingent screening for Trisomy 21: does it make a difference? A comparative study with real data

NC Prodan, C Wiechers, A Geipel, A Walter… - Fetal Diagnosis and …, 2022 - karger.com
Objective: The aim of the objective was to compare the detection rate for trisomy 21 of
universal cell free DNA (cfDNA) screening with contingent screening. Methods …

A single center experience of prenatal parent‐fetus trio exome sequencing for pregnancies with congenital anomalies

A Dufke, M Hoopmann, S Waldmüller… - Prenatal …, 2022 - Wiley Online Library
Objectives To examine the diagnostic yield of trio exome sequencing in fetuses with multiple
structural defects with no pathogenic findings in cytogenetic and microarray analyses …

First‐trimester ductus venosus velocity ratio as a marker of major cardiac defects

P Wagner, K Eberle, J Sonek, C Berg… - … in Obstetrics & …, 2019 - Wiley Online Library
Objectives To examine ductus venosus (DV) flow in fetuses with and those without a cardiac
defect and to evaluate different phases of DV flow in addition to the standard assessment of …

[HTML][HTML] Obesity in prenatal medicine: a game changer?

NC Prodan, M Schmidt, M Hoopmann, H Abele… - Archives of Gynecology …, 2023 - Springer
Obesity is recognized by the World Health Organization (WHO) as a disease in its own right.
Moreover, obesity is an increasingly concerning public health issue across the world and its …

Dosing interval between mifepristone and misoprostol in second and third trimester termination

N Prodan, J Breisch, M Hoopmann, H Abele… - Archives of Gynecology …, 2019 - Springer
Objective To compare several strategies for second trimester labor induction for termination
of pregnancy (TOP) using misoprostol and mifepristone and to determine which one is more …