Aims Our study aims to investigate the pathophysiologic mechanism underlying tako-tsubo
cardiomyopathy using F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) …

Metabolic syndrome is a risk factor for cardiovascular disease. The aim of the present study
was to identify genetic variants that confer susceptibility to atherothrombotic cerebral …

Epigenetic modification, particularly changes in DNA methylation at gene promoters, is
implicated in the pathogenesis of atherosclerosis. However, the analysis of DNA methylation …

Early‑onset cardiovascular and renal diseases have a strong genetic component. In the
present study, exome‑wide association studies (EWASs) were performed to identify genetic …

Although various genes that confer susceptibility to myocardial infarction (MI) have been
identified for Caucasian populations in genome-wide association studies (GWAS), genetic …

Various loci and genes that confer susceptibility to coronary artery disease (CAD) have been
identified mainly in Caucasian populations by genome‑wide association studies (GWASs) …

Background Although genome-wide association studies (GWASs) have implicated several
genes in the predisposition to chronic kidney disease (CKD) in Caucasian or African …

Atrial fibrillation (AF) may result from an electric conduction disturbance, increased
hemodynamic stress, ischemia, inflammation, or remodeling in atria. Although genetic …

Angioplasty and stenting is the primary treatment for flow-limiting atherosclerosis; however,
this strategy is limited by pathological vascular remodeling. Using a systems approach, we …

Background Left atrial (LA) conduction velocity (CV) is an electrical remodeling parameter of
atrial fibrillation (AF) substrate. However, the pathophysiological substrate of LA-CV and its …