The androgen receptor (AR) plays a crucial role in normal physiology, development and
metabolism as well as in the aetiology and treatment of diverse pathologies such as …

The number of publications in the field of chemical cross-linking combined with mass
spectrometry (XL-MS) to derive constraints for protein three-dimensional structure modeling …

Globins constitute a superfamily of proteins widespread in all kingdoms of life, where they
fulfill multiple functions, such as efficient O2 transport and modulation of nitric oxide …

Abstract The Hha and TomB proteins from Escherichia coli form an oxygen-dependent toxin–
antitoxin (TA) system. Here we show that YmoB, the Yersinia orthologue of TomB, and its …

Background Vertebrate CPEB proteins bind mRNAs at cytoplasmic polyadenylation
elements (CPEs) in their 3′ UTRs, leading to cytoplasmic changes in their poly (A) tail …

Light-regulated drugs allow remotely photoswitching biological activity and enable plausible
therapies based on small molecules. However, only freely diffusible photochromic ligands …

Intrinsically disordered regions (IDRs) are preferred sites for post‐translational modifications
essential for regulating protein function. The enhanced local mobility of IDRs facilitates their …

COVID-19 pathophysiology is currently not fully understood, reliable prognostic factors
remain elusive, and few specific therapeutic strategies have been proposed. In this scenario …

T lymphocytes mediate cellular and humoral defense against foreign bodies or
autoantigens. An understanding of T-cell information processing furthers studies of the …

Brain-derived amyloid-β (Aβ) dimers are associated with Alzheimer's disease (AD).
However, their covalent nature remains controversial. This feature is relevant, as a covalent …