Gene map of the extended human MHC
R Horton, L Wilming, V Rand, RC Lovering… - Nature Reviews …, 2004 - nature.com
The major histocompatibility complex (MHC) is the most important region in the vertebrate
genome with respect to infection and autoimmunity, and is crucial in adaptive and innate …
genome with respect to infection and autoimmunity, and is crucial in adaptive and innate …
[PDF][PDF] Polygenic risk scores for prediction of breast cancer and breast cancer subtypes
N Mavaddat, K Michailidou, J Dennis, M Lush… - The American Journal of …, 2019 - cell.com
Stratification of women according to their risk of breast cancer based on polygenic risk
scores (PRSs) could improve screening and prevention strategies. Our aim was to develop …
scores (PRSs) could improve screening and prevention strategies. Our aim was to develop …
Sensory hair cell regeneration in the zebrafish lateral line
ME Lush, T Piotrowski - Developmental Dynamics, 2014 - Wiley Online Library
Background: Damage or destruction of sensory hair cells in the inner ear leads to hearing or
balance deficits that can be debilitating, especially in older adults. Unfortunately, the …
balance deficits that can be debilitating, especially in older adults. Unfortunately, the …
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
…, L McGuffog, D Barrowdale, A Lee, S Healey, M Lush… - Nature …, 2013 - nature.com
TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed∼ 480 …
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed∼ 480 …
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
Genome-wide association studies (GWAS) and large-scale replication studies have
identified common variants in 79 loci associated with breast cancer, explaining∼ 14% of the …
identified common variants in 79 loci associated with breast cancer, explaining∼ 14% of the …
The DNA sequence and biological annotation of human chromosome 1
SG Gregory, KF Barlow, KE McLay, R Kaul… - Nature, 2006 - nature.com
The reference sequence for each human chromosome provides the framework for
understanding genome function, variation and evolution. Here we report the finished …
understanding genome function, variation and evolution. Here we report the finished …
[PDF][PDF] Guidelines for human gene nomenclature
HM Wain, EA Bruford, RC Lovering, MJ Lush… - Genomics, 2002 - genenames.org
Guidelines for human gene nomenclature were first published in 1979 [1], when the Human
Gene Nomenclature Committee was first given the authority to approve and implement …
Gene Nomenclature Committee was first given the authority to approve and implement …
[PDF][PDF] The HUGO gene nomenclature committee (HGNC)
OMIM, SWISS-PROT, HGMD, GDB, GENATLAS, GeneCards), where each symbol is
unambiguously associated with a single gene. Use of approved symbols greatly increases …
unambiguously associated with a single gene. Use of approved symbols greatly increases …
Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth
The inability of CNS axons to regenerate after traumatic spinal cord injury is due, in part, to
the inhibitory effects of myelin. The three major previously identified constituents of this …
the inhibitory effects of myelin. The three major previously identified constituents of this …
genenames. org: the HGNC resources in 2011
RL Seal, SM Gordon, MJ Lush, MW Wright… - Nucleic acids …, 2010 - academic.oup.com
Abstract The HUGO Gene Nomenclature Committee (HGNC) aims to assign a unique gene
symbol and name to every human gene. The HGNC database currently contains almost 30 …
symbol and name to every human gene. The HGNC database currently contains almost 30 …