Effect of mastication on regional cerebral blood flow in humans examined by positron-emission tomography with 15O-labelled water and magnetic resonance imaging

…, M Senda, K Kubota, Y Sato, M Funakoshi… - Archives of oral …, 1997 - Elsevier
The interaction between mastication and cerebral blood flow was studied in 12 healthy
volunteers (five males and seven females) aged 18–40 years. Positron-emission …

[HTML][HTML] Anti-apoptotic role of focal adhesion kinase (FAK): induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a …

Y Sonoda, Y Matsumoto, M Funakoshi… - Journal of Biological …, 2000 - ASBMB
Focal adhesion kinase (FAK) has an anti-apoptotic role in anchorage-dependent cells via an
unknown mechanism. To elucidate the role of FAK in anti-apoptosis, we have established …

[HTML][HTML] Oxidative stress causes heart failure with impaired mitochondrial respiration

H Nojiri, T Shimizu, M Funakoshi, O Yamaguchi… - Journal of Biological …, 2006 - ASBMB
Elderly people insidiously manifest the symptoms of heart failure, such as dyspnea and/or
physical disabilities in an age-dependent manner. Although previous studies suggested that …

Budding yeast Dsk2p is a polyubiquitin-binding protein that can interact with the proteasome

M Funakoshi, T Sasaki, T Nishimoto… - Proceedings of the …, 2002 - National Acad Sciences
Dsk2p from Saccharomyces cerevisiae belongs to the class of proteins that contain a
ubiquitin-like (UbL) domain at the N terminus together with a ubiquitin-associated (UBA) …

[PDF][PDF] Heterohexameric ring arrangement of the eukaryotic proteasomal ATPases: implications for proteasome structure and assembly

RJ Tomko, M Funakoshi, K Schneider, J Wang… - Molecular cell, 2010 - cell.com
The proteasome has a paramount role in eukaryotic cell regulation. It consists of a
proteolytic core particle (CP) bound to one or two regulatory particles (RPs). Each RP is …

[HTML][HTML] Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base

M Funakoshi, RJ Tomko, H Kobayashi, M Hochstrasser - Cell, 2009 - cell.com
The central protease of eukaryotes, the 26S proteasome, has a 20S proteolytic core particle
(CP) and an attached 19S regulatory particle (RP). The RP is further subdivided into lid and …

A multimeric assembly factor controls the formation of alternative 20S proteasomes

AR Kusmierczyk, MJ Kunjappu, M Funakoshi… - Nature structural & …, 2008 - nature.com
The proteasome is the central regulatory protease of eukaryotic cells. Heteroheptameric α-
subunit and β-subunit rings stack to form the 20S proteasome, which associates with a 19S …

The resonant interaction between a long internal gravity wave and a surface gravity wave packet

M Funakoshi, M Oikawa - Journal of the Physical Society of Japan, 1983 - journals.jps.jp
The long-short wave interactions between an internal gravity wave and a surface gravity
wave packet in a two-layer fluid are investigated. When the phase speed of the internal …

Emerin and cardiomyopathy in Emery–Dreifuss muscular dystrophy

M Funakoshi, Y Tsuchiya, K Arahata - Neuromuscular Disorders, 1999 - Elsevier
Emery–Dreifuss muscular dystrophy (EDMD) is an inherited disorder characterized by the
clinical triad of life-threatening progressive cardiomyopathy with conduction defect, early …

Amiloride inhibition of responses of rat single chorda tympani fibers to chemical and electrical tongue stimulations

Y Ninomiya, M Funakoshi - Brain research, 1988 - Elsevier
Amiloride inhibition of single fiber responses of the rat chorda tympani to ionic chemical and
electrical tongue stimulations was studied. Amiloride reduced responses to both chemical …