Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11. 2

T Thye, FO Vannberg, SH Wong, E Owusu-Dabo… - Nature …, 2010 - nature.com
We combined two tuberculosis genome-wide association studies from Ghana and The
Gambia with subsequent replication in a combined 11,425 individuals. rs4331426, located …

ALOX5 variants associated with susceptibility to human pulmonary tuberculosis

F Herb, T Thye, S Niemann, ENL Browne… - Human molecular …, 2008 - academic.oup.com
Abstract The 5-lipoxygenase (ALOX5)-derived lipid mediators leukotrienes and lipoxins
have regulatory functions in inflammation by modulating activities of immune cells and …

Inadvertent exposure of pregnant women to ivermectin and albendazole during mass drug administration for lymphatic filariasis

JO Gyapong, MA Chinbuah… - Tropical Medicine & …, 2003 - Wiley Online Library
The current strategy for the interruption of transmission of lymphatic filariasis in areas where
the disease is co‐endemic with onchocerciasis is repeated annual mass treatment of …

[HTML][HTML] IL10 Haplotype Associated with Tuberculin Skin Test Response but Not with Pulmonary TB

T Thye, EN Browne, MA Chinbuah, J Gyapong, I Osei… - PLoS …, 2009 - journals.plos.org
Evidence from genetic association and twin studies indicates that susceptibility to
tuberculosis (TB) is under genetic control. One gene implicated in susceptibility to TB is that …

[HTML][HTML] Variant G57E of Mannose Binding Lectin Associated with Protection against Tuberculosis Caused by Mycobacterium africanum but not by M. tuberculosis

T Thye, S Niemann, K Walter, S Homolka… - PloS one, 2011 - journals.plos.org
Structural variants of the Mannose Binding Lectin (MBL) cause quantitative and qualitative
functional deficiencies, which are associated with various patterns of susceptibility to …

[HTML][HTML] Treatment choices for fevers in children under-five years in a rural Ghanaian district

J Nonvignon, MKS Aikins, MA Chinbuah, M Abbey… - Malaria Journal, 2010 - Springer
Background Health care demand studies help to examine the behaviour of individuals and
households during illnesses. Few of existing health care demand studies examine the …

[HTML][HTML] Impact of community management of fever (using antimalarials with or without antibiotics) on childhood mortality: a cluster-randomized controlled trial in …

MA Chinbuah, PA Kager, M Abbey… - The American journal …, 2012 - ncbi.nlm.nih.gov
Malaria and pneumonia are leading causes of childhood mortality. Home Management of
fever as Malaria (HMM) enables presumptive treatment with antimalarial drugs but excludes …

The Species Mycobacterium africanum in the Light of New Molecular Markers

S Niemann, T Kubica, FC Bange, O Adjei… - Journal of clinical …, 2004 - Am Soc Microbiol
The findings of recent studies addressing the molecular characteristics of Mycobacterium
tuberculosis complex isolates have initiated a discussion on the classification of M …

MCP-1 promoter variant −362C associated with protection from pulmonary tuberculosis in Ghana, West Africa

T Thye, S Nejentsev, CD Intemann… - Human Molecular …, 2009 - academic.oup.com
Current endeavour focuses on human genetic factors that contribute to susceptibility to or
protection from tuberculosis (TB). Monocytes are crucial in containing Mycobacterium …

Factors related to retention of community health workers in a trial on community-based management of fever in children under 5 years in the Dangme West District of …

M Abbey, LK Bartholomew, J Nonvignon… - International …, 2014 - academic.oup.com
Background In resource-constrained settings of developing countries, promotion of
community-based health interventions through community health workers (CHWs) is an …