Research over the past 20years indicates that adolescent sex offenders account for a
significant number of child sexual abuse perpetrators. Studies indicate that this group has a …

Point mutations of the CACNA1A gene coding for the α 1A voltage-dependent calcium
channel subunit are responsible for familial hemiplegic migraine (FHM) and episodic ataxia …

Autosomal dominant spinocerebellar ataxias (SCAs) are genetically heterogeneous
neurological disorders characterized by cerebellar dysfunction mostly due to Purkinje cell …

Background Increased body mass index and weight gain are risk factors for psoriasis, and
the prevalence of obesity in patients with psoriasis is higher than in the general population …

Adolescent sexual offenders have recently been the focus of a number of research studies
that have indicated that sexual offending often begins in adolescence and that prior sexual …

Abstract Familial Adult Myoclonic Epilepsy (FAME) is characterised by cortical myoclonic
tremor usually from the second decade of life and overt myoclonic or generalised tonic …

Familial adult myoclonus epilepsy (FAME) is a genetic epilepsy syndrome that for many
years has resisted understanding of its underlying molecular cause. This review covers the …

Chorea is a hyperkinetic movement disorder resulting from dysfunction of striatal medium
spiny neurons (MSNs), which form the main output projections from the basal ganglia. Here …

Familial hemiplegic migraine, episodic ataxia type 2 (EA2), and spinocerebellar ataxia type
6 are allelic disorders of the CACNA1A gene (coding for the α 1A subunit of P/Q calcium …

Introduction ADCY5 mutations have been recently identified as an important cause of early-
onset hyperkinetic movement disorders. The phenotypic spectrum associated with mutations …