Purpose Endometrial cancers have long been divided into estrogen-dependent type I and
the less common clinically aggressive estrogen-independent type II. Little is known about …

BACKGROUND & AIMS: Heritable factors contribute to the development of colorectal
cancer. Identifying the genetic loci associated with colorectal tumor formation could …

The search for the causes of cancer and means of cancer prevention has entered a new era
as recent developments allow correlation of environmental and behavioural exposures …

Background: Breast cancer incidence rates have historically been 4–7 times higher in the
United States than in China or Japan, although the reasons remain elusive. When Chinese …

Population stratification refers to differences in allele frequencies between cases and
controls due to systematic differences in ancestry rather than association of genes with …

Familial clustering studies indicate that breast cancer risk has a substantial genetic
component,,. To identify new breast cancer risk variants, we genotyped approximately …

Background Previous studies have suggested that breast cancer risk factors are associated
with estrogen receptor (ER) and progesterone receptor (PR) expression status of the tumors …

The authors describe the design and implementation of a large multiethnic cohort
established to study diet and cancer in the United States. They detail the source of the …

In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-
wide association studies, we observed large chromosomal abnormalities in a subset of …

After the recent discovery that common genetic variation in 8q24 influences inherited risk of
prostate cancer, we genotyped 2,973 SNPs in up to 7,518 men with and without prostate …