User profiles for "author:L Boccuto"

Luigi Boccuto

Clinical Associate Professor, Clemson University
Verified email at clemson.edu
Cited by 4200

[HTML][HTML] Gut microbiota and obesity: a role for probiotics

L Abenavoli, E Scarpellini, C Colica, L Boccuto… - Nutrients, 2019 - mdpi.com
Nowadays, obesity is one of the most prevalent human health problems. Research from the
last 30 years has clarified the role of the imbalance between energy intake and expenditure …

[HTML][HTML] Diet and non-alcoholic fatty liver disease: the Mediterranean way

L Abenavoli, L Boccuto, A Federico, M Dallio… - International journal of …, 2019 - mdpi.com
Lifestyle interventions remain the first-line treatment for non-alcoholic fatty liver disease
(NAFLD), even if the optimal alimentary regimen is still controversial. The interest in …

[HTML][HTML] Dietary polyphenols and non-alcoholic fatty liver disease

…, T Larussa, A Corea, AC Procopio, L Boccuto… - Nutrients, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD), which is emerging as a major public health issue
worldwide, is characterized by a wide spectrum of liver disorders, ranging from simple fat …

[HTML][HTML] Prevalence of SHANK3 variants in patients with different subtypes of autism spectrum disorders

L Boccuto, M Lauri, SM Sarasua, CD Skinner… - European Journal of …, 2013 - nature.com
Autism spectrum disorders (ASDs) include three main conditions: autistic disorder (AD),
pervasive developmental disorder, not otherwise specified (PDD-NOS), and Asperger …

A multi-strain probiotic reduces the fatty liver index, cytokines and aminotransferase levels in NAFLD patients: evidence from a randomized clinical trial

…, G Mykhalchyshyn, L Kononenko, L Boccuto… - 2018 - ir.librarynmu.com
BACKGROUND: Probiotics have a beneficial effect on nonalcoholic fatty liver disease
(NAFLD) in animal models. Randomized placebo-controlled trials (RCTs) in NAFLD are still …

Clinical and genomic evaluation of 201 patients with Phelan–McDermid syndrome

SM Sarasua, L Boccuto, JL Sharp, A Dwivedi, CF Chen… - Human genetics, 2014 - Springer
This study is the first to describe age-related changes in a large cohort of patients with
Phelan–McDermid syndrome (PMS), also known as 22q13 deletion syndrome. Over a follow …

[HTML][HTML] PIK3CA-associated developmental disorders exhibit distinct classes of mutations with variable expression and tissue distribution

…, N Martin, M McKinnon, MC Addor, L Boccuto… - JCI insight, 2016 - ncbi.nlm.nih.gov
Mosaicism is increasingly recognized as a cause of developmental disorders with the
advent of next-generation sequencing (NGS). Mosaic mutations of PIK3CA have been …

A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein …

L Boccuto, K Aoki, H Flanagan-Steet… - Human molecular …, 2014 - academic.oup.com
Abstract 'Salt & Pepper'syndrome is an autosomal recessive condition characterized by
severe intellectual disability, epilepsy, scoliosis, choreoathetosis, dysmorphic facial features …

[HTML][HTML] Decreased tryptophan metabolism in patients with autism spectrum disorders

L Boccuto, CF Chen, AR Pittman, CD Skinner… - Molecular autism, 2013 - Springer
Abstract Background Autism spectrum disorders (ASDs) are relatively common
neurodevelopmental conditions whose biological basis has been incompletely determined …

[HTML][HTML] Controlling false discoveries in high-dimensional situations: boosting with stability selection

B Hofner, L Boccuto, M Göker - BMC bioinformatics, 2015 - Springer
Background Modern biotechnologies often result in high-dimensional data sets with many
more variables than observations (n≪ p). These data sets pose new challenges to statistical …