The use of AlloDerm in postmastectomy alloplastic breast reconstruction: part II. A cost analysis

LA Jansen, SA Macadam - Plastic and reconstructive surgery, 2011 - journals.lww.com
Background: Increasingly, AlloDerm is being used in alloplastic breast reconstruction, and
has been the subject of a recent systematic review. The authors' objective was to perform a …

The use of AlloDerm in postmastectomy alloplastic breast reconstruction: part I. A systematic review

LA Jansen, SA Macadam - Plastic and reconstructive surgery, 2011 - journals.lww.com
Background: Postmastectomy alloplastic breast reconstruction is a common procedure that
continues to evolve. Increasingly, AlloDerm is being used in both direct-to-implant and two …

The evidence base for the acellular dermal matrix AlloDerm: a systematic review

LA Jansen, P De Caigny, NA Guay… - Annals of plastic …, 2013 - journals.lww.com
Background Many decellularized dermal matrices are available with various applications, all
with slight differences. AlloDerm appears to have the greatest presence in the literature. The …

PI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasia

LA Jansen, GM Mirzaa, GE Ishak, BJ O'Roak, JB Hiatt… - Brain, 2015 - academic.oup.com
Malformations of cortical development containing dysplastic neuronal and glial elements,
including hemimegalencephaly and focal cortical dysplasia, are common causes of …

Association of MTOR mutations with developmental brain disorders, including megalencephaly, focal cortical dysplasia, and pigmentary mosaicism

GM Mirzaa, CD Campbell, N Solovieff, CP Goold… - JAMA …, 2016 - jamanetwork.com
Importance Focal cortical dysplasia (FCD), hemimegalencephaly, and megalencephaly
constitute a spectrum of malformations of cortical development with shared neuropathologic …

Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model

M Wong, KC Ess, EJ Uhlmann, LA Jansen… - Annals of …, 2003 - Wiley Online Library
Excessive astrocytosis in cortical tubers in tuberous sclerosis complex (TSC) suggests that
astrocytes may be important for epileptogenesis in TSC. We previously demonstrated that …

Novel mutations in ATP1A3 associated with catastrophic early life epilepsy, episodic prolonged apnea, and postnatal microcephaly

AR Paciorkowski, SS McDaniel, LA Jansen, H Tully… - …, 2015 - Wiley Online Library
Summary Objective Mutations of ATP 1A3 have been associated with rapid onset dystonia‐
parkinsonism and more recently with alternating hemiplegia of childhood. Here we report …

[HTML][HTML] Unrealistic optimism in early-phase oncology trials

LA Jansen, PS Appelbaum, WMP Klein, ND Weinstein… - Irb, 2011 - ncbi.nlm.nih.gov
Early-phase oncology trials are vital for developing new and more effective therapies for
treating cancers. While it is possible that some of these trials provide benefit to …

[HTML][HTML] Untargeted metabolomics and infrared ion spectroscopy identify biomarkers for pyridoxine-dependent epilepsy

UFH Engelke, RE Van Outersterp… - The Journal of …, 2021 - Am Soc Clin Investig
Background Pyridoxine-dependent epilepsy (PDE-ALDH7A1) is an inborn error of lysine
catabolism that presents with refractory epilepsy in newborns. Biallelic ALDH7A1 variants …

Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex

LH Zeng, Y Ouyang, V Gazit, JR Cirrito, LA Jansen… - Neurobiology of …, 2007 - Elsevier
Mice with inactivation of the Tuberous sclerosis complex-1 (Tsc1) gene in glia
(Tsc1GFAPCKO mice) have deficient astrocyte glutamate transporters and develop seizures …