[HTML][HTML] Early diagnosis of dementia
KS Santacruz, D Swagerty - American Family Physician, 2001 - aafp.org
Until recently, the most significant issue facing a family physician regarding the diagnosis
and treatment of dementia was ruling out delirium and potentially treatable etiologies …
and treatment of dementia was ruling out delirium and potentially treatable etiologies …
Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L)
M Ramsden, L Kotilinek, C Forster… - Journal of …, 2005 - Soc Neuroscience
Here, we describe the generation of a novel transgenic mouse model of human tauopathy.
The rTg (tauP301L) 4510 mouse expresses the P301L mutation in tau (4R0N) associated …
The rTg (tauP301L) 4510 mouse expresses the P301L mutation in tau (4R0N) associated …
Posterior reversible encephalopathy syndrome: incidence of atypical regions of involvement and imaging findings
AM McKinney, J Short, CL Truwit… - American Journal of …, 2007 - Am Roentgen Ray Soc
OBJECTIVE. Posterior reversible encephalopathy syndrome (PRES) is classically
characterized as symmetric parietooccipital edema but may occur in other distributions with …
characterized as symmetric parietooccipital edema but may occur in other distributions with …
Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy
TL Spires, JD Orne, K SantaCruz, R Pitstick… - The American journal of …, 2006 - Elsevier
Neurofibrillary tangles form in a specific spatial and temporal pattern in Alzheimer's disease.
Although tangle formation correlates with dementia and neuronal loss, it remains unknown …
Although tangle formation correlates with dementia and neuronal loss, it remains unknown …
Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury
BW Festoff, S Ameenuddin, PM Arnold… - Journal of …, 2006 - Wiley Online Library
Minocycline, a clinically used tetracycline for over 40 years, crosses the blood–brain barrier
and prevents caspase up‐regulation. It reduces apoptosis in mouse models of Huntington's …
and prevents caspase up‐regulation. It reduces apoptosis in mouse models of Huntington's …
Hippocampal sclerosis in advanced age: clinical and pathological features
Hippocampal sclerosis is a relatively common neuropathological finding (∼ 10% of
individuals over the age of 85 years) characterized by cell loss and gliosis in the …
individuals over the age of 85 years) characterized by cell loss and gliosis in the …
Acute toxic leukoencephalopathy: potential for reversibility clinically and on MRI with diffusion-weighted and FLAIR imaging
AM McKinney, SA Kieffer, RT Paylor… - American Journal of …, 2009 - Am Roentgen Ray Soc
OBJECTIVE. Toxic leukoencephalopathy may present acutely or subacutely with
symmetrically reduced diffusion in the periventricular and supraventricular white matter …
symmetrically reduced diffusion in the periventricular and supraventricular white matter …
De novo Induction of Genetically Engineered Brain Tumors in Mice Using Plasmid DNA
SM Wiesner, SA Decker, JD Larson, K Ericson… - Cancer research, 2009 - AACR
Spontaneous mouse models of cancer show promise to more accurately recapitulate human
disease and predict clinical efficacy. Transgenic mice or viral vectors have been required to …
disease and predict clinical efficacy. Transgenic mice or viral vectors have been required to …
[HTML][HTML] Chronic traumatic encephalopathy in athletes involved with high-impact sports
C Safinia, EM Bershad, HB Clark… - Journal of vascular …, 2016 - ncbi.nlm.nih.gov
Background and purpose Chronic traumatic encephalopathy (CTE) is a neurodegenerative
disease occurring most commonly in athletes and is caused by repeated concussive or …
disease occurring most commonly in athletes and is caused by repeated concussive or …
Regional NAD (P) H: quinone oxidoreductase activity in Alzheimer's disease
KS SantaCruz, E Yazlovitskaya, J Collins… - Neurobiology of …, 2004 - Elsevier
Converging evidence supports the role of oxidative stress in the pathology of Alzheimer's
disease (AD). This notion is further supported by recent findings of increased NAD (P) H …
disease (AD). This notion is further supported by recent findings of increased NAD (P) H …