Functional partnerships between proteins are at the core of complex cellular phenotypes,
and the networks formed by interacting proteins provide researchers with crucial scaffolds …

Abstract Changes in gene expression are thought to underlie many of the phenotypic
differences between species. However, large-scale analyses of gene expression evolution …

The identification of orthologous genes forms the basis for most comparative genomics
studies. Existing approaches either lack functional annotation of the identified orthologous …

Background Maturity-onset of the young (MODY) is a clinically heterogeneous form of
diabetes characterized by an autosomal-dominant mode of inheritance, an onset before the …

The identification of orthologous relationships forms the basis for most comparative
genomics studies. Here, we present the second version of the eggNOG database, which …

As a result of sex chromosome differentiation from ancestral autosomes, male mammalian
cells only contain one X chromosome. It has long been hypothesized that X-linked gene …

Among the numerous introductions to Lacan published to date in English, Philippe Julien's
work is certainly outstanding. Beyond its conceptual clarity the book constitutes an excellent …

The free propagation of isobaric flames through aluminum dust clouds is investigated in an
extensive series of experiments using two facilities with different scales. In small-scale …

Objective Single gene mutations leading to severe obesity have so far been identified in 3‐
5% cases in European populations. However, prevalence of these pathogenic mutations …

The properties of genotype–phenotype landscapes are crucial for understanding evolution
but are not characterized for most traits. Here, we present a> 95% complete local landscape …