Recommendations for somatic and germline genetic testing of single pheochromocytoma and paraganglioma based on findings from a series of 329 patients

M Currás-Freixes, L Inglada-Pérez… - Journal of medical …, 2015 - jmg.bmj.com
Background Nowadays, 65–80% of pheochromocytoma and paraganglioma (PPGL) cases
are explained by germline or somatic mutations in one of 22 genes. Several genetic testing …

[HTML][HTML] PheoSeq: a targeted next-generation sequencing assay for pheochromocytoma and paraganglioma diagnostics

M Currás-Freixes, E Piñeiro-Yañez… - The Journal of Molecular …, 2017 - Elsevier
Genetic diagnosis is recommended for all pheochromocytoma and paraganglioma (PPGL)
cases, as driver mutations are identified in approximately 80% of the cases. As the list of …

[HTML][HTML] Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/mTOR axis in metastatic pheochromocytoma …

B Calsina, LJ Castro-Vega, R Torres-Pérez… - Theranostics, 2019 - ncbi.nlm.nih.gov
Abstract Rationale: Pheochromocytomas and paragangliomas (PPGLs) are rare
neuroendocrine tumors that present variable outcomes. To date, no effective therapies or …

VEGF, VEGFR3, and PDGFRB Protein Expression Is Influenced by RAS Mutations in Medullary Thyroid Carcinoma

V Mancikova, L Inglada-Pérez, M Curras-Freixes… - Thyroid, 2014 - liebertpub.com
Background: Tyrosine kinase inhibitors (TKIs) have achieved remarkable clinical results in
medullary thyroid carcinoma (MTC) patients. However, the considerable variability in patient …

[HTML][HTML] Low-dose radioiodine ablation in patients with low-risk differentiated thyroid cancer

GAJ Londoño, AMG Vicente, JS Marcos… - European Thyroid …, 2018 - etj.bioscientifica.com
Aim: Based on the response criteria of the 2015 American Thyroid Associations guidelines,
our objectives were to determine the response rate when using a low dose of 131-I GBq in …

All-cause mortality and risk factors in patients with type 1 diabetes in Castilla-La Mancha, Spain. DIACAM1 2010–2020 study

PJP Corrales, JS Marcos, GL Gallardo… - Primary Care …, 2024 - Elsevier
Introduction Despite better treatments and care for patients with type 1 diabetes (T1DM), all-
cause and cardiovascular mortality still remains higher compared to the general population …

Reference values and universal screening of thyroid function in the first trimester of the population of pregnant women in Toledo (Spain).

J Sastre-Marcos, F Val-Zaballos… - … y Nutricion: Organo …, 2015 - europepmc.org
Reference values and universal screening of thyroid function in the first trimester of the
population of pregnant women in Toledo (Spain). - Abstract - Europe PMC Sign in | Create an …

BRAF V600E positive papillary thyroid carcinoma is associated with suspicious ultrasound features

J Sastre-Marcos, F Del Val-Zaballos… - Endocrine …, 2015 - endocrine-abstracts.org
Aims: To study if BRAF V600E mutation in thyroid fine needle aspiration (FNA) is associated
with specific ultrasound (US) characteristics. Patients and methods: From 2010 to 2014 we …

Control metabólico y de factores de riesgo cardiovascular en una cohorte de pacientes con diabetes mellitus. Resultados a los 4 años

OL Iglesias, JS Marcos, VP Cortés, AL Pazos… - Endocrinología y …, 2012 - Elsevier
Objetivos Valorar el grado de control glucémico y del resto de factores de riesgo
cardiovascular en una cohorte de pacientes diabéticos seguidos en consultas externas …

Carcinoma diferenciado de tiroides: supervivencia y factores relacionados

J Sastre Marcos, O Llamazares Iglesias… - … . nutr.(Ed. impr.), 2011 - pesquisa.bvsalud.org
Antecedentes y objetivo El cáncer diferenciado de tiroides (CDT) es el tumor endocrino más
frecuente, con buen pronóstico y supervivencias superiores al 85%. El objetivo de nuestro …