Variants of uncertain significance in BRCA1 and BRCA2 assessment of in silico analysis and a proposal for communication in genetic counselling

S Moghadasi, N Hofland, JN Wouts… - Journal of medical …, 2013 - jmg.bmj.com
Background Nearly 15% of BRCA1 and BRCA2 DNA tests lead to the identification of
Variants of Uncertain Significance (VUS). VUS are classified in the Netherlands according to …