[HTML][HTML] Peyer's patches: the immune sensors of the intestine
The gut-associated lymphoid tissue (GALT) consists of isolated or aggregated lymphoid
follicles forming Peyer's patches (PPs). By their ability to transport luminal antigens and …
follicles forming Peyer's patches (PPs). By their ability to transport luminal antigens and …
Biodiversity in helminths and nematodes as a field of study: an overview
Despite their potential negative effects, parasites may be used as targets for biological
conservation and studies on the evolutionary and ecological impact of parasitism. These …
conservation and studies on the evolutionary and ecological impact of parasitism. These …
Crohn's disease: the cold chain hypothesis
JP Hugot, C Alberti, D Berrebi, E Bingen, JP Cézard - The Lancet, 2003 - thelancet.com
Crohn's disease is the result of an abnormal immune response of the gut mucosa triggered
by one or more environmental risk factors in people with predisposing gene variations …
by one or more environmental risk factors in people with predisposing gene variations …
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
JP Hugot, M Chamaillard, H Zouali, S Lesage… - Nature, 2001 - nature.com
Crohn's disease, and ulcerative colitis, the two main types of chronic inflammatory bowel
disease, are multifactorial conditions of unknown aetiology. A susceptibility locus for Crohn's …
disease, are multifactorial conditions of unknown aetiology. A susceptibility locus for Crohn's …
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
We undertook a meta-analysis of six Crohn's disease genome-wide association studies
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
Several risk factors for Crohn's disease have been identified in recent genome-wide
association studies. To advance gene discovery further, we combined data from three …
association studies. To advance gene discovery further, we combined data from three …
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis …
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis …
Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease
FM Ruemmele, G Veres, KL Kolho… - Journal of Crohn's …, 2014 - academic.oup.com
Children and adolescents with Crohn's disease (CD) present often with a more complicated
disease course compared to adult patients. In addition, the potential impact of CD on growth …
disease course compared to adult patients. In addition, the potential impact of CD on growth …
[PDF][PDF] The NLR gene family: a standard nomenclature
Immune regulatory proteins such as CIITA, NAIP, IPAF, NOD1, NOD2, NALP1, and cryopyrin
(also known as NALP3) are members of a family characterized by the presence of a NACHT …
(also known as NALP3) are members of a family characterized by the presence of a NACHT …
Mapping of a susceptibility locus for Crohn's disease on chromosome 16
JP Hugot, P Laurent-Puig, C Gower-Rousseau… - Nature, 1996 - nature.com
Abstract CROHN'S disease (CD) and ulcerative colitis are the major forms of chronic
inflammatory bowel diseases in the western world, and occur in young adults with an …
inflammatory bowel diseases in the western world, and occur in young adults with an …