[HTML][HTML] Peyer's patches: the immune sensors of the intestine

C Jung, JP Hugot, F Barreau - International journal of inflammation, 2010 - hindawi.com
The gut-associated lymphoid tissue (GALT) consists of isolated or aggregated lymphoid
follicles forming Peyer's patches (PPs). By their ability to transport luminal antigens and …

Biodiversity in helminths and nematodes as a field of study: an overview

JP Hugot, P Baujard, S Morand - Nematology, 2001 - brill.com
Despite their potential negative effects, parasites may be used as targets for biological
conservation and studies on the evolutionary and ecological impact of parasitism. These …

Crohn's disease: the cold chain hypothesis

JP Hugot, C Alberti, D Berrebi, E Bingen, JP Cézard - The Lancet, 2003 - thelancet.com
Crohn's disease is the result of an abnormal immune response of the gut mucosa triggered
by one or more environmental risk factors in people with predisposing gene variations …

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

JP Hugot, M Chamaillard, H Zouali, S Lesage… - Nature, 2001 - nature.com
Crohn's disease, and ulcerative colitis, the two main types of chronic inflammatory bowel
disease, are multifactorial conditions of unknown aetiology. A susceptibility locus for Crohn's …

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

A Franke, DPB McGovern, JC Barrett, K Wang… - Nature …, 2010 - nature.com
We undertook a meta-analysis of six Crohn's disease genome-wide association studies
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

JC Barrett, S Hansoul, DL Nicolae, JH Cho, RH Duerr… - Nature …, 2008 - nature.com
Several risk factors for Crohn's disease have been identified in recent genome-wide
association studies. To advance gene discovery further, we combined data from three …

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

CA Anderson, G Boucher, CW Lees, A Franke… - Nature …, 2011 - nature.com
Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis …

Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease

FM Ruemmele, G Veres, KL Kolho… - Journal of Crohn's …, 2014 - academic.oup.com
Children and adolescents with Crohn's disease (CD) present often with a more complicated
disease course compared to adult patients. In addition, the potential impact of CD on growth …

[PDF][PDF] The NLR gene family: a standard nomenclature

JPY Ting, RC Lovering, ES Alnemri, J Bertin, JM Boss… - Immunity, 2008 - cell.com
Immune regulatory proteins such as CIITA, NAIP, IPAF, NOD1, NOD2, NALP1, and cryopyrin
(also known as NALP3) are members of a family characterized by the presence of a NACHT …

Mapping of a susceptibility locus for Crohn's disease on chromosome 16

JP Hugot, P Laurent-Puig, C Gower-Rousseau… - Nature, 1996 - nature.com
Abstract CROHN'S disease (CD) and ulcerative colitis are the major forms of chronic
inflammatory bowel diseases in the western world, and occur in young adults with an …