HLA and infectious diseases

JM Blackwell, SE Jamieson… - Clinical microbiology …, 2009 - Am Soc Microbiol
Following their discovery in the early 1970s, classical human leukocyte antigen (HLA) loci
have been the prototypical candidates for genetic susceptibility to infectious disease …

[HTML][HTML] SLC11A1 (formerly NRAMP1) and disease resistance

JM Blackwell, T Goswami, CAW Evans… - Cellular …, 2001 - ncbi.nlm.nih.gov
Slc11a1 (formerly Nramp1) has many pleiotropic effects on macrophage (m) activation,
including regulation of the CXC chemokine KC, interleukin-1β (IL-1β), inducible nitric oxide …

[HTML][HTML] Genetic susceptibility to infectious diseases: big is beautiful, but will bigger be even better?

D Burgner, SE Jamieson, JM Blackwell - The Lancet infectious …, 2006 - thelancet.com
Genetic epidemiology, including twin studies, provides robust evidence that genetic
variation in human populations contributes to susceptibility to infectious disease. One of the …

The Genome of the Kinetoplastid Parasite, Leishmania major

AC Ivens, CS Peacock, EA Worthey, L Murphy… - Science, 2005 - science.org
Leishmania species cause a spectrum of human diseases in tropical and subtropical
regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase …

[HTML][HTML] Genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

A Strange, F Capon, CCA Spencer, J Knight… - Nature …, 2010 - ncbi.nlm.nih.gov
(WTCCC2) consortia is provided in the Supplementary Note online. Author Contributions
FC, ADB, CEMG, J. Kere., A. Reis, JNB and RCT oversaw cohort collection for both the …

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

Australo-Anglo-American Spondyloarthritis … - Nature …, 2011 - nature.com
Ankylosing spondylitis is a common form of inflammatory arthritis predominantly affecting the
spine and pelvis that occurs in approximately 5 out of 1,000 adults of European descent …

[PDF][PDF] Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes

DM Ruderfer, S Ripke, A McQuillin, J Boocock… - Cell, 2018 - cell.com
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology.
Understanding the genetic factors contributing to the shared and disorder-specific symptoms …

Studies on the Mechanism of B(C6F5)3-Catalyzed Hydrosilation of Carbonyl Functions

DJ Parks, JM Blackwell, WE Piers - The Journal of organic …, 2000 - ACS Publications
The strong organoborane Lewis acid B (C6F5) 3 catalyzes the hydrosilation (using R3SiH)
of aromatic and aliphatic carbonyl functions at convenient rates with loadings of 1− 4%. For …

Memory illusions: Recalling, recognizing, and recollecting events that never occurred

DG Payne, CJ Elie, JM Blackwell… - Journal of Memory and …, 1996 - Elsevier
Three experiments that document a powerful false memory effect in recall and recognition
are reported. Subjects studied lists of items related to critical nonpresented themes (eg …

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

International Stroke Genetics Consortium (ISGC)… - Nature …, 2012 - nature.com
Genetic factors have been implicated in stroke risk, but few replicated associations have
been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke …