Metastasis remains a leading cause of cancer mortality due to the lack of specific inhibitors
against this complex process. To identify compounds selectively targeting the metastatic …

Background Centralization of complex surgical care has led patients to travel longer
distances. Emerging evidence suggested a negative association between increased travel …

Introduction Hereditary diffuse gastric cancer (HDGC) is a cancer syndrome associated with
variants in E-cadherin (CDH1), diffuse gastric cancer and lobular breast cancer. There is …

Background Chronic granulomatous disease (CGD) is a rare genetic disorder causing
recurrent infections. More than one-quarter of patients develop hepatic abscesses and liver …

Despite its declining incidence, gastric cancer (GC) remains a leading cause of cancer-
related deaths worldwide. A multimodal approach to GC is critical to ensure optimal patient …

Prostate cancer (PCa) frequently develops antiapoptotic mechanisms and acquires
resistance to anticancer drugs. Therefore, identifying PCa drug resistance determinants …

The rates of gastric cancer, which is the third leading cause of cancer-related deaths
worldwide, vary depending on geographic location. Margin-negative gastrectomy and …

Background Despite the near universal occurrence of activating codon 12 KRAS somatic
variants in pancreatic cancer, there is considerable heterogeneity in the molecular make-up …

Background Tyrosine kinase inhibitors (TKI) have become the guideline-recommended
therapy for high-risk resected and advanced gastrointestinal stromal tumors (GISTs). Exon …

Background Considering that several different specialties perform nerve decompressions in
the upper extremity, universal technical standards do not exist. Many of these procedures …