The mammalian HSP90 family of proteins is a cluster of highly conserved molecules that are
involved in myriad cellular processes. Their distribution in various cellular compartments …

The maintenance of oxygen homeostasis in human tissues is mediated by several cellular
adaptations in response to low-oxygen stress, called hypoxia. A decrease in tissue oxygen …

Our current view on biological membranes has gradually evolved from the influential fluid
mosaic model of the early 1970s to a distinctively more complex picture. Biological …

Background: Pharmacokinetic studies have shown that the small intestine is the major site of
absorption for many flavonoid glucosides. Flavonoids are generally present as glycosylated …

The central aspect of epithelial cells is their polarized structure, characterized by two distinct
domains of the plasma membrane, the apical and the basolateral membrane. Apical protein …

Human maltase-glucoamylase (MGAM) and sucrase-isomaltase (SI) are small intestinal
enzymes that work concurrently to hydrolyze the mixture of linear α-1, 4-and branched α-1, 6 …

The primary target of severe acute respiratory syndrome-associated coronavirus (SARS-
CoV) is epithelial cells in the respiratory and intestinal tract. The cellular receptor for SARS …

Cholesterol present in the plasma membrane of target cells has been shown to be important
for the infection by SARS-CoV. We show that cholesterol depletion by treatment with methyl …

Objective IBS is a common gut disorder of uncertain pathogenesis. Among other factors,
genetics and certain foods are proposed to contribute. Congenital sucrase–isomaltase …

The plasma membrane of polarised epithelial cells is characterised by two structurally and
functionally different domains, the apical and basolateral domains. These domains contain …