User profiles for "author:Harriet Feilotter"
Harriet FeilotterQueen's University, Department of Pathology and Molecular Medicine Verified email at queensu.ca Cited by 4866 |
[HTML][HTML] EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer
Background The epithelial to mesenchymal transition (EMT) is a molecular process through
which an epithelial cell undergoes transdifferentiation into a mesenchymal phenotype. The …
which an epithelial cell undergoes transdifferentiation into a mesenchymal phenotype. The …
[HTML][HTML] MicroRNA-193b represses cell proliferation and regulates cyclin D1 in melanoma
Cutaneous melanoma is an aggressive form of human skin cancer characterized by high
metastatic potential and poor prognosis. To better understand the role of microRNAs …
metastatic potential and poor prognosis. To better understand the role of microRNAs …
An international, multicentered, evidence-based reappraisal of genes reported to cause congenital long QT syndrome
A Adler, V Novelli, AS Amin, E Abiusi, M Care… - Circulation, 2020 - Am Heart Assoc
Background: Long QT syndrome (LQTS) is the first described and most common inherited
arrhythmia. Over the last 25 years, multiple genes have been reported to cause this …
arrhythmia. Over the last 25 years, multiple genes have been reported to cause this …
Analysis of PTEN and the 10q23 region in primary prostate carcinomas
Deletions involving chromosome 10q23 occur frequently in prostatic carcinomas. Recently,
a novel tumour suppressor gene, PTEN, mapping to this interval, has been identified …
a novel tumour suppressor gene, PTEN, mapping to this interval, has been identified …
Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect
A susceptibility gene on chromosome 18 and a parent-of-origin effect have been suggested
for bipolar affective disorder (BPAD). We have studied 28 nuclear families selected for …
for bipolar affective disorder (BPAD). We have studied 28 nuclear families selected for …
[HTML][HTML] MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes
Antidepressants (ADs) are the most common treatment for major depressive disorder (MDD).
However, only∼ 30% of patients experience adequate response after a single AD trial, and …
However, only∼ 30% of patients experience adequate response after a single AD trial, and …
[HTML][HTML] Discovering biomarkers for antidepressant response: protocol from the Canadian biomarker integration network in depression (CAN-BIND) and clinical …
Abstract Background Major Depressive Disorder (MDD) is among the most prevalent and
disabling medical conditions worldwide. Identification of clinical and biological markers …
disabling medical conditions worldwide. Identification of clinical and biological markers …
[HTML][HTML] The microRNA-200 family is upregulated in endometrial carcinoma
J Snowdon, X Zhang, T Childs, VA Tron, H Feilotter - PloS one, 2011 - journals.plos.org
Background MicroRNAs (miRNAs, miRs) are small non-coding RNAs that negatively
regulate gene expression at the post-transcriptional level. MicroRNAs are dysregulated in …
regulate gene expression at the post-transcriptional level. MicroRNAs are dysregulated in …
Evaluation of gene validity for CPVT and short QT syndrome in sudden arrhythmic death
Aims Catecholaminergic polymorphic ventricular tachycardia (CPVT) and short QT
syndrome (SQTS) are inherited arrhythmogenic disorders that can cause sudden death …
syndrome (SQTS) are inherited arrhythmogenic disorders that can cause sudden death …
[HTML][HTML] miR-193b regulates Mcl-1 in melanoma
J Chen, X Zhang, C Lentz, M Abi-Daoud… - The American journal of …, 2011 - Elsevier
MicroRNAs play important roles in gene regulation, and their expression is frequently
dysregulated in cancer cells. In a previous study, we reported that miR-193b represses cell …
dysregulated in cancer cells. In a previous study, we reported that miR-193b represses cell …