Peutz–Jeghers syndrome (PJS, MIM175200) is an autosomal dominant condition defined by
the development of characteristic polyps throughout the gastrointestinal tract and …

Lynch syndrome (hereditary non-polyposis colorectal cancer) is characterised by the
development of colorectal cancer, endometrial cancer and various other cancers, and is …

Abstract In 1994, the International Collaborative Group on Hereditary Nonpolyposis
Colorectal Cancer (ICG-HNPCC) established an international database of mutations …

Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is a
common autosomal dominant syndrome characterized by early age at onset, neoplastic …

New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome)
proposed by the International Collaborative Group on HNPCC - ScienceDirect Skip to main …

H ereditary non-polyposis colorectal cancer (HNPCC) accounts for 5-10 percent of all the
cases of colorectal adenocarcinoma. Because of the paucity of carefully investigated and …

Background Observational studies report reduced colorectal cancer in regular aspirin
consumers. Randomised controlled trials have shown reduced risk of adenomas but none …

BACKGROUND & AIMS: Hereditary nonpolyposis colorectal cancer is characterized by early-
onset colorectal cancer and the occurrence of various other cancers. The recent isolation of …

Lynch syndrome (LS) is characterised by the development of colorectal cancer, endometrial
cancer and various other cancers, and is caused by a mutation in one of the mismatch repair …

Background: Familial adenomatous polyposis (FAP) is a well-described inherited syndrome,
which is responsible for< 1% of all colorectal cancer (CRC) cases. The syndrome is …