The hypermobile type of Ehlers–Danlos syndrome (hEDS) is likely the most common
hereditary disorder of connective tissue. It has been described largely in those with …

The Ehlers–Danlos syndromes (EDS) are a clinically and genetically heterogeneous group
of heritable connective tissue disorders (HCTDs) characterized by joint hypermobility, skin …

B cells play an important role in the pathogenesis of many autoimmune diseases. Selective
targeting of these cells has been recently achieved using a chimeric monoclonal antibody …

Purpose: Ehlers–Danlos syndrome (EDS) comprises a group of overlapping hereditary
disorders of connective tissue with significant morbidity and mortality, including major …

Purpose Currently, 31 patients with classical-like EDS (clEDS) due to tenascin-X deficiency
have been reported in the literature. We report on the clinical and molecular characteristics …

The genetically determined rheumatological connective tissue disorders constitute a group
of phenotypically related inherited conditions caused by aberrations in genes encoding for …

Background The Ehlers-Danlos syndromes (EDS) are a group of connective tissue disorders
with several recognised types. Patients with a type of EDS have connective tissue …

Background The Ehlers-Danlos syndromes (EDS) are heritable disorders of connective
tissue (HDCT), reclassified in the 2017 nosology into 13 subtypes. The genetic basis for …

Discussion The case highlights an unusual presentation of a condition that is highly
prevalent but under-diagnosed. 3 Stress incontinence in a nulliparous woman is an unusual …

Objectives The multisystemic comorbid symptoms/conditions of hypermobility spectrum
disorders (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS) often significantly affect …