The joint—gut axis in inflammatory bowel diseases

LKPM Brakenhoff, DM van der Heijde… - Journal of Crohn's …, 2010 - academic.oup.com
Inflammatory bowel diseases, Crohn's disease and ulcerative colitis, are associated with a
variety of extraintestinal manifestations. The most common extraintestinal manifestation …

Determinants of health-related quality of life in Crohn's disease: a systematic review and meta-analysis

M van der Have, KS van der Aalst… - Journal of Crohn's …, 2014 - academic.oup.com
Background and aims Understanding the determinants of Crohn's disease (CD) patients'
health-related quality of life (HRQOL) may facilitate interventions that improve HRQOL …

Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study

M Duijvestein, ACW Vos, H Roelofs, ME Wildenberg… - Gut, 2010 - gut.bmj.com
Background and aim Mesenchymal stromal cells (MSCs) are pluripotent cells that have
immunosuppressive effects both in vitro and in experimental colitis. Promising results of …

Healthcare costs of inflammatory bowel disease have shifted from hospitalisation and surgery towards anti-TNFα therapy: results from the COIN study

ME van der Valk, MJJ Mangen, M Leenders, G Dijkstra… - Gut, 2014 - gut.bmj.com
Objective The introduction of anti tumour necrosis factor-α (anti-TNFα) therapy might impact
healthcare expenditures, but there are limited data regarding the costs of inflammatory …

[HTML][HTML] Low rates of adherence for tumor necrosis factor-α inhibitors in Crohn's disease and rheumatoid arthritis: results of a systematic review

HH Fidder, MMJ Singendonk… - World journal of …, 2013 - ncbi.nlm.nih.gov
AIM: To investigate adherence rates in tumor necrosis factor-α (TNF-α)-inhibitors in Crohn's
disease (CD) and rheumatoid arthritis (RA) by systematic review of medical literature …

Identification of patients with variants in TPMT and dose reduction reduces hematologic events during thiopurine treatment of inflammatory bowel disease

MJH Coenen, DJ de Jong, CJ van Marrewijk… - Gastroenterology, 2015 - Elsevier
Background & Aims More than 20% of patients with inflammatory bowel disease (IBD)
discontinue thiopurine therapy because of severe adverse drug reactions (ADRs); …

Allicin inhibits spontaneous and TNF-α induced secretion of proinflammatory cytokines and chemokines from intestinal epithelial cells

A Lang, M Lahav, E Sakhnini, I Barshack, HH Fidder… - Clinical nutrition, 2004 - Elsevier
Background & aims: Allicin, the active substance of fresh crushed garlic has different
biological activities and was implicated as an anti-inflammatory agent. Epithelial cells have …

Genotype–phenotype correlations in Peutz-Jeghers syndrome

CI Amos, MB Keitheri-Cheteri, M Sabripour… - Journal of medical …, 2004 - jmg.bmj.com
Background and aims: Peutz-Jeghers syndrome (PJS) is a dominantly inherited disorder
often caused by mutations in STK11. Time to onset of symptoms was characterised for a …

Quality of web-based information on inflammatory bowel diseases

S van der Marel, M Duijvestein… - Inflammatory bowel …, 2009 - academic.oup.com
Background The Internet is the largest source of health information and is widely used by
inflammatory bowel disease (IBD) patients. As information is largely unregulated, our …

[HTML][HTML] Evolution of costs of inflammatory bowel disease over two years of follow-up

ME van der Valk, MJJ Mangen, M Severs… - PLoS …, 2016 - journals.plos.org
Background With the increasing use of anti-TNF therapy in inflammatory bowel disease
(IBD), a shift of costs has been observed with medication costs replacing hospitalization and …