Unrelated donor and HLA‐identical sibling haematopoietic stem cell transplantation cure chronic granulomatous disease with good long‐term outcome and growth
E Soncini, MA Slatter, LBKR Jones… - British journal of …, 2009 - Wiley Online Library
Chronic granulomatous disease (CGD) causes recurrent infection and inflammatory
disease. Despite antimicrobial prophylaxis, patients experience frequent hospitalisations …
disease. Despite antimicrobial prophylaxis, patients experience frequent hospitalisations …
International harmonization in performing and reporting minimal residual disease assessment in multiple myeloma trials
Minimal residual disease (MRD) assessment is incorporated in an increasing number of
multiple myeloma (MM) clinical trials as a correlative analysis, an endpoint or even as a …
multiple myeloma (MM) clinical trials as a correlative analysis, an endpoint or even as a …
[HTML][HTML] First-line treatment with zoledronic acid as compared with clodronic acid in multiple myeloma (MRC Myeloma IX): a randomised controlled trial
Background Bisphosphonates reduce the risk of skeletal events in patients with malignant
bone disease, and zoledronic acid has shown potential anticancer effects in preclinical and …
bone disease, and zoledronic acid has shown potential anticancer effects in preclinical and …
[HTML][HTML] Mutational spectrum, copy number changes, and outcome: results of a sequencing study of patients with newly diagnosed myeloma
Purpose At the molecular level myeloma is characterised by copy number abnormalities and
recurrent translocations into the immunoglobulin heavy chain (IGH) locus. Novel …
recurrent translocations into the immunoglobulin heavy chain (IGH) locus. Novel …
The role of maintenance thalidomide therapy in multiple myeloma: MRC Myeloma IX results and meta-analysis
GJ Morgan, WM Gregory, FE Davies… - Blood, The Journal …, 2012 - ashpublications.org
Thalidomide maintenance has the potential to modulate residual multiple myeloma (MM)
after an initial response. This trial compared the effect of thalidomide maintenance and no …
after an initial response. This trial compared the effect of thalidomide maintenance and no …
Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
Understanding the profile of oncogene and tumor suppressor gene mutations with their
interactions and impact on the prognosis of multiple myeloma (MM) can improve the …
interactions and impact on the prognosis of multiple myeloma (MM) can improve the …
[PDF][PDF] Minimal residual disease assessed by multiparameter flow cytometry in multiple myeloma: impact on outcome in the Medical Research Council Myeloma IX …
AC Rawstron, JA Child, RM de Tute, FE Davies… - J Clin …, 2013 - researchgate.net
Minimal Residual Disease Assessed by Multiparameter Flow Cytometry in Multiple Myeloma:
Impact on Outcome in the Medical Researc Page 1 Minimal Residual Disease Assessed by …
Impact on Outcome in the Medical Researc Page 1 Minimal Residual Disease Assessed by …
[HTML][HTML] A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis
Patients with newly diagnosed multiple myeloma (NDMM) with high-risk disease are in need
of new treatment strategies to improve the outcomes. Multiple clinical, cytogenetic, or gene …
of new treatment strategies to improve the outcomes. Multiple clinical, cytogenetic, or gene …
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia
MC Di Bernardo, D Crowther-Swanepoel, P Broderick… - Nature …, 2008 - nature.com
We conducted a genome-wide association study of 299,983 tagging SNPs for chronic
lymphocytic leukemia (CLL) and performed validation in two additional series totaling 1,529 …
lymphocytic leukemia (CLL) and performed validation in two additional series totaling 1,529 …
A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial
KD Boyd, FM Ross, L Chiecchio, GP Dagrada, ZJ Konn… - Leukemia, 2012 - nature.com
The association of genetic lesions detected by fluorescence in situ hybridization (FISH) with
survival was analyzed in 1069 patients with newly presenting myeloma treated in the …
survival was analyzed in 1069 patients with newly presenting myeloma treated in the …