User profiles for "author:Frauke Zipp"
Frauke ZippProfessor of Neurology, University Medical Center of the Johannes Gutenberg Verified email at unimedizin-mainz.de Cited by 31306 |
The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases
F Zipp, O Aktas - Trends in neurosciences, 2006 - cell.com
Classical knowledge distinguishes between inflammatory and non-inflammatory diseases of
the brain. Either the immune system acts on the CNS and initiates a damage cascade, as in …
the brain. Either the immune system acts on the CNS and initiates a damage cascade, as in …
Mechanisms of disease: aquaporin-4 antibodies in neuromyelitis optica
Neuromyelitis optica (NMO) is a rare CNS inflammatory disorder that predominantly affects
the optic nerves and spinal cord. Recent serological findings strongly suggest that NMO is a …
the optic nerves and spinal cord. Recent serological findings strongly suggest that NMO is a …
Immunoneuropsychiatry—novel perspectives on brain disorders
Immune processes have a vital role in CNS homeostasis, resilience and brain reserve. Our
cognitive and social abilities rely on a highly sensitive and fine-tuned equilibrium of immune …
cognitive and social abilities rely on a highly sensitive and fine-tuned equilibrium of immune …
ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis
X Montalban, R Gold, AJ Thompson… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background: Multiple sclerosis (MS) is a complex disease with new drugs becoming
available in the past years. There is a need for a reference tool compiling current data to aid …
available in the past years. There is a need for a reference tool compiling current data to aid …
[PDF][PDF] Genetic cell ablation reveals clusters of local self-renewing microglia in the mammalian central nervous system
During early embryogenesis, microglia arise from yolk sac progenitors that populate the
developing central nervous system (CNS), but how the tissue-resident macrophages are …
developing central nervous system (CNS), but how the tissue-resident macrophages are …
[HTML][HTML] Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database
More than 800 published genetic association studies have implicated dozens of potential
risk loci in Parkinson's disease (PD). To facilitate the interpretation of these findings, we …
risk loci in Parkinson's disease (PD). To facilitate the interpretation of these findings, we …
Sirt1 contributes critically to the redox-dependent fate of neural progenitors
T Prozorovski, U Schulze-Topphoff, R Glumm… - Nature cell …, 2008 - nature.com
Repair processes that are activated in response to neuronal injury, be it inflammatory,
ischaemic, metabolic, traumatic or other cause, are characterized by a failure to replenish …
ischaemic, metabolic, traumatic or other cause, are characterized by a failure to replenish …
Green tea epigallocatechin-3-gallate mediates T cellular NF-κB inhibition and exerts neuroprotection in autoimmune encephalomyelitis
O Aktas, T Prozorovski, A Smorodchenko… - The Journal of …, 2004 - journals.aai.org
Recent studies in multiple sclerosis and its animal model, experimental autoimmune
encephalomyelitis (EAE), point to the fact that even in the early phase of inflammation …
encephalomyelitis (EAE), point to the fact that even in the early phase of inflammation …
[PDF][PDF] In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis
Neuronal damage in autoimmune neuroinflammation is the correlate for long-term disability
in multiple sclerosis (MS) patients. Here, we investigated the role of immune cells in …
in multiple sclerosis (MS) patients. Here, we investigated the role of immune cells in …
MR-elastography reveals degradation of tissue integrity in multiple sclerosis
In multiple sclerosis (MS), diffuse brain parenchymal damage exceeding focal inflammation
is increasingly recognized to be present from the very onset of the disease, and, although …
is increasingly recognized to be present from the very onset of the disease, and, although …