The parallel fiber-Purkinje cell (PF-PC) synapse represents the point of maximal signal
divergence in the cerebellar cortex with an estimated number of about 60 billion synaptic …

Purkinje cell (PC) dysfunction or degeneration is the most frequent finding in animal models
with ataxic symptoms. Mutations affecting intrinsic membrane properties can lead to ataxia …

Autosomal dominant spinocerebellar ataxias (SCAs) are genetically heterogeneous
neurological disorders characterized by cerebellar dysfunction mostly due to Purkinje cell …

The role of the cerebellum in Alzheimer's disease (AD) has been neglected for a long time.
Recent studies carried out using transgenic mouse models have demonstrated that amyloid …

To better understand learning mechanisms, one needs to study synaptic plasticity induced
by behavioral training. Recently, it has been demonstrated that the cerebellum is involved in …

Since a growing number of studies based on the real-time reverse transcriptase polymerase
chain reaction (RT-PCR) continue to be published in order to highlight genes specifically …

Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by
impaired social interaction, isolated areas of interest, and insistence on sameness …

Spinocerebellar ataxias (SCAs) are a heterogeneous group of autosomal-dominant
neurodegenerative disorders involving the cerebellum and 23 different genes. We mapped …

NG2‐expressing cells comprise a population of cycling precursors that can exit the cell cycle
and differentiate into mature oligodendrocytes. As a whole, they display heterogeneous …

Resurgent currents are functionally crucial in sustaining the high frequency firing of
cerebellar Purkinje neurons expressing Na v 1.6 channels. β-Scorpion toxins, such as …