User profiles for "author:Filippo Tempia"
Filippo TempiaProfessor of Physiology, University of Torino Verified email at unito.it Cited by 3947 |
[HTML][HTML] Modulation, plasticity and pathophysiology of the parallel fiber-purkinje cell synapse
E Hoxha, F Tempia, P Lippiello… - Frontiers in synaptic …, 2016 - frontiersin.org
The parallel fiber-Purkinje cell (PF-PC) synapse represents the point of maximal signal
divergence in the cerebellar cortex with an estimated number of about 60 billion synaptic …
divergence in the cerebellar cortex with an estimated number of about 60 billion synaptic …
[HTML][HTML] Purkinje cell signaling deficits in animal models of ataxia
Purkinje cell (PC) dysfunction or degeneration is the most frequent finding in animal models
with ataxic symptoms. Mutations affecting intrinsic membrane properties can lead to ataxia …
with ataxic symptoms. Mutations affecting intrinsic membrane properties can lead to ataxia …
Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28
Autosomal dominant spinocerebellar ataxias (SCAs) are genetically heterogeneous
neurological disorders characterized by cerebellar dysfunction mostly due to Purkinje cell …
neurological disorders characterized by cerebellar dysfunction mostly due to Purkinje cell …
[HTML][HTML] The emerging role of altered cerebellar synaptic processing in Alzheimer's disease
E Hoxha, P Lippiello, F Zurlo, I Balbo… - Frontiers in aging …, 2018 - frontiersin.org
The role of the cerebellum in Alzheimer's disease (AD) has been neglected for a long time.
Recent studies carried out using transgenic mouse models have demonstrated that amyloid …
Recent studies carried out using transgenic mouse models have demonstrated that amyloid …
[PDF][PDF] Long-term synaptic changes induced in the cerebellar cortex by fear conditioning
To better understand learning mechanisms, one needs to study synaptic plasticity induced
by behavioral training. Recently, it has been demonstrated that the cerebellum is involved in …
by behavioral training. Recently, it has been demonstrated that the cerebellum is involved in …
Selection of reference genes for quantitative real-time RT-PCR studies in mouse brain
E Boda, A Pini, E Hoxha, R Parolisi… - Journal of Molecular …, 2009 - Springer
Since a growing number of studies based on the real-time reverse transcriptase polymerase
chain reaction (RT-PCR) continue to be published in order to highlight genes specifically …
chain reaction (RT-PCR) continue to be published in order to highlight genes specifically …
[HTML][HTML] Autistic-like traits and cerebellar dysfunction in Purkinje cell PTEN knock-out mice
D Cupolillo, E Hoxha, A Faralli, A De Luca… - …, 2016 - nature.com
Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by
impaired social interaction, isolated areas of interest, and insistence on sameness …
impaired social interaction, isolated areas of interest, and insistence on sameness …
[HTML][HTML] ELOVL5 mutations cause spinocerebellar ataxia 38
Spinocerebellar ataxias (SCAs) are a heterogeneous group of autosomal-dominant
neurodegenerative disorders involving the cerebellum and 23 different genes. We mapped …
neurodegenerative disorders involving the cerebellum and 23 different genes. We mapped …
The GPR17 receptor in NG2 expressing cells: Focus on in vivocell maturation and participation in acute trauma and chronic damage
NG2‐expressing cells comprise a population of cycling precursors that can exit the cell cycle
and differentiate into mature oligodendrocytes. As a whole, they display heterogeneous …
and differentiate into mature oligodendrocytes. As a whole, they display heterogeneous …
[HTML][HTML] Resurgent current and voltage sensor trapping enhanced activation by a β-scorpion toxin solely in Nav1. 6 channel: significance in mice Purkinje neurons
E Schiavon, T Sacco, RR Cassulini, G Gurrola… - Journal of biological …, 2006 - ASBMB
Resurgent currents are functionally crucial in sustaining the high frequency firing of
cerebellar Purkinje neurons expressing Na v 1.6 channels. β-Scorpion toxins, such as …
cerebellar Purkinje neurons expressing Na v 1.6 channels. β-Scorpion toxins, such as …