User profiles for "author:E Espín"

Estefanía Espín

Ph.D. student, University of British Columbia
Verified email at hli.ubc.ca
Cited by 113

[HTML][HTML] Cellular and molecular biomarkers of long COVID: a scoping review

E Espín, C Yang, CP Shannon, S Assadian, D He… - …, 2023 - thelancet.com
Summary Background Long-COVID (LC) encompasses diverse symptoms lasting months
after the initial SARS-CoV-2 infection. Symptoms can be debilitating and affect the quality of …

β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer

…, SR Cajal, S Schwartz Jr, A Vivancos, E Espín… - Nature medicine, 2012 - nature.com
The Wnt–β-catenin and PI3K-AKT-FOXO3a pathways have a central role in cancer. AKT
phosporylates FOXO3a, relocating it from the cell nucleus to the cytoplasm, an effect that is …

BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes

…, C Oliveira, P Alhopuro, C Moutinho, E Espín… - Oncogene, 2005 - nature.com
Recently, it was shown that the oncogenic activation of BRAF, a member of the RAS/RAF
family of kinases, by the V600E mutation is characteristic for sporadic colon tumors with …

BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency

…, M Pinto, A Duval, C Brennetot, E Domingo, E Espín… - Oncogene, 2003 - nature.com
Genes from the RAF family are Ras-regulated kinases involved in growth cellular responses.
Recently, a V599E hotspot mutation within the BRAF gene was reported in a high …

Use of a prosthetic mesh to prevent parastomal hernia during laparoscopic abdominoperineal resection: a randomized controlled trial

…, M Martí, LM Jiménez, M Armengol-Carrasco, E Espín - Hernia, 2012 - Springer
Purpose Prevention of parastomal hernia represents an important aim when a permanent
stoma is necessary. The objective of this work is to assess whether implantation of a …

Delphi consensus statement: quality indicators for inflammatory bowel disease comprehensive care units

…, B Casis, E Domenech, E Espín… - Journal of Crohn's …, 2014 - academic.oup.com
Background and aims While it is commonly accepted that Inflammatory bowel disease (IBD)
Comprehensive Care Units (ICCUs) facilitate the delivery of quality care to Crohn's disease …

Preventing parastomal hernia using a modified Sugarbaker technique with composite mesh during laparoscopic abdominoperineal resection: a randomized controlled …

…, A Serracant, E Kreisler, S Biondo, E Espín… - 2016 - journals.lww.com
Objective: The aim of this study was to assess the reduction in the incidence of parastomal
hernia (PH) after placement of prophylactic synthetic mesh using a modified Sugarbaker …

Oncological outcome following anastomotic leak in rectal surgery

E Espín, MA Ciga, M Pera, H Ortiz, J Lujan… - Journal of British …, 2015 - academic.oup.com
Background The influence of anastomotic leak on local recurrence and survival remains
debated in rectal cancer. Methods This was a multicentre observational study using data …

A personalized preclinical model to evaluate the metastatic potential of patient-derived colon cancer initiating cells

…, L Mendizabal, D Moreno, R Charco, E Espín… - Clinical Cancer …, 2013 - AACR
Purpose: Within the aim of advancing precision oncology, we have generated a collection of
patient-derived xenografts (PDX) characterized at the molecular level, and a preclinical …

Association of SARS-CoV-2 infection and persistence with long COVID

C Yang, H Zhao, E Espín, SJ Tebbutt - The Lancet Respiratory …, 2023 - thelancet.com
Long COVID or post-COVID-19 condition can affect anyone exposed to SARS-CoV-2,
regardless of age or severity of the original symptoms, characterised by long-term health …