A Lancet Commission on 70 years of women's reproductive, maternal, newborn, child, and adolescent health in China
Executive summary Women's reproductive, maternal, newborn, child, and adolescent health
(RMNCAH) is a cornerstone for the healthy development of the next generation and a …
(RMNCAH) is a cornerstone for the healthy development of the next generation and a …
[HTML][HTML] m6A modification: a double-edged sword in tumor development
R Gao, M Ye, B Liu, M Wei, D Ma, K Dong - Frontiers in Oncology, 2021 - frontiersin.org
Modification of m6A, as the most abundant mRNA modification, plays diverse roles in
various biological processes in eukaryotes. Emerging evidence has revealed that m6A …
various biological processes in eukaryotes. Emerging evidence has revealed that m6A …
Maternal mosaicism is a significant contributor to discordant sex chromosomal aneuploidies associated with noninvasive prenatal testing
BACKGROUND: In the human fetus, sex chromosome aneuploidies (SCAs) are as prevalent
as the common autosomal trisomies 21, 18, and 13. Currently, most noninvasive prenatal …
as the common autosomal trisomies 21, 18, and 13. Currently, most noninvasive prenatal …
The cell growth suppressor, mir-126, targets IRS-1
J Zhang, Y Du, Y Lin, Y Chen, L Yang, H Wang… - … and biophysical research …, 2008 - Elsevier
miRNAs are a family of approximately 22-nuleotide-long noncoding RNAs involved in the
formation and progress of tumors. Since traditional methods for the detection of miRNAs …
formation and progress of tumors. Since traditional methods for the detection of miRNAs …
[HTML][HTML] Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression
M Weng, W Chen, X Chen, H Lu, Z Sun, Q Yu… - Nature …, 2020 - nature.com
Evidence suggests that fasting exerts extensive antitumor effects in various cancers,
including colorectal cancer (CRC). However, the mechanism behind this response is …
including colorectal cancer (CRC). However, the mechanism behind this response is …
[HTML][HTML] The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes
HS Ryu, SY Park, D Ma, J Zhang, W Lee - PloS one, 2011 - journals.plos.org
Background Mitochondrial dysfunction induces insulin resistance in myocytes via a
reduction of insulin receptor substrate-1 (IRS-1) expression. However, the effect of …
reduction of insulin receptor substrate-1 (IRS-1) expression. However, the effect of …
[HTML][HTML] miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10
Y Chen, J Zhang, H Wang, J Zhao, C Xu, Y Du, X Luo… - BMC cancer, 2012 - Springer
Background miRNAs are a group of small RNA molecules regulating target genes by
inducing mRNA degradation or translational repression. Aberrant expression of miRNAs …
inducing mRNA degradation or translational repression. Aberrant expression of miRNAs …
[HTML][HTML] Proteomic analysis of seminal plasma from asthenozoospermia patients reveals proteins that affect oxidative stress responses and semen quality
J Wang, J Wang, HR Zhang, HJ Shi, D Ma… - Asian journal of …, 2009 - ncbi.nlm.nih.gov
Asthenozoospermia (AS) is a common cause of human male infertility. In one study, more
than 80% of the samples from infertile men had reduced sperm motility. Seminal plasma is a …
than 80% of the samples from infertile men had reduced sperm motility. Seminal plasma is a …
Comprehensive expression profiling of microRNAs in laryngeal squamous cell carcinoma
P Cao, L Zhou, J Zhang, F Zheng, H Wang, D Ma… - Head & …, 2013 - Wiley Online Library
Background MicroRNAs (miRNAs) are noncoding RNAs involved in posttranscriptional
regulation of gene expression in cancer and provide new perspectives on the development …
regulation of gene expression in cancer and provide new perspectives on the development …
Paternal ethanol exposure and behavioral abnormities in offspring: associated alterations in imprinted gene methylation
F Liang, L Diao, J Liu, N Jiang, J Zhang, H Wang… - …, 2014 - Elsevier
Research confirms that maternal ethanol (EtOH) exposure can induce physical and mental
disorders in offspring, yet the effect of paternal ethanol exposure on offspring is unclear …
disorders in offspring, yet the effect of paternal ethanol exposure on offspring is unclear …