Three topics affecting cobalamin, folate, and homocysteine that have generated interest,
activity, and advances in recent years are discussed. These are:(I) the application of an …

Cytotoxic T lymphocytes (CTLs) have a central role in the successful control of
immunodeficiency virus infection. Evasion of this immune response through CTL escape is …

The recent failure of the T-cell-based HIV vaccine trial led by Merck & Co., Inc. prompts the
urgent need to refocus on the question of which T-cell responses are required to control HIV …

Patient-derived organoids (PDOs) have recently emerged as robust preclinical models;
however, their potential to predict clinical outcomes in patients has remained unclear. We …

A significantly revised and improved introduction to a critical aspect of scientific computation
Matrix computations lie at the heart of most scientific computational tasks. For any scientist or …

How Chinese students and their teachers see the context and content of their learning is
explored in the essays in this collection. Seeing these students in their own cultural …

Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections
are characterized by early peaks of viraemia that decline as strong cellular immune …

Background Rheumatic heart disease remains an important preventable cause of
cardiovascular death and disability, particularly in low-income and middle-income countries …

The major histocompatibility complex (MHC) has been given different names in different
species (Klein 1986). It is designated H-2 in the mouse, HLA in humans, B in the domestic …

Developing an immunogen that elicits broadly neutralizing antibodies (bNAbs) is an elusive
but important goal of HIV vaccine research, especially after the recent failure of the leading T …