The liver is responsible for many metabolic, endocrine and exocrine functions.
Approximately 2 million deaths per year are associated with liver failure. Modern 3D …

Background Liver organoid technology holds great promises to be used in large-scale
population-based drug screening and in future regenerative medicine strategies. Recently …

Liver transplantation from compatible donors has been the main therapy available for
patients with irreversible hepatic injuries. Due to the increasing shortage of organs suitable …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with no cure. The
reports showed the role of nearby astrocytes around the motor neurons as one among the …

Despite advances in the identification and characterization of endophytic bacteria in various
plant species worldwide, little is known about such microorganisms in plants from the …

Objective Astrocytes play a significant role in the pathology of multiple sclerosis (MS).
Nevertheless, for ethical reasons, most studies in these cells were performed using the …

Familial idiopathic basal ganglia calcification, also known as “Fahr's disease”(FD), is a
neuropsychiatric disorder with autosomal dominant pattern of inheritance and characterized …

Amyotrophic lateral sclerosis type 8 (ALS8) is an autosomal dominant form of ALS, which is
caused by pathogenic variants in the VAPB gene. Here we investigated five ALS8 patients …

A homozygous mutation in the inositol monophosphatase 1 (IMPA1) gene was recently
identified in nine individuals with severe intellectual disability (ID) and disruptive behavior …

Chromoanagenesis is a descriptive term that encompasses classes of catastrophic
mutagenic processes that generate localized and complex chromosome rearrangements in …